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(S)-1-Boc-3-methylpiperazine

(S)-1-Boc-3-methylpiperazine structure

CAS No.: 147081-29-6

Chemical Name:: (S)-1-Boc-3-methylpiperazine

Synonyms: tert-butyl (S)-3-methylpiperazine-1-carboxylate;(S)-1-BOC-3-METHYLPIPERAZINE;(S)-TERT-BUTYL 3-METHYLPIPERAZINE-1-CARBOXYLATE;(S)-4-Boc-2-methylpiperazine;4-HYDROXY-7-METHOXYQUINOLINE-2-CARBOXYLIC ACID;4-Hydroxy-7-methoxy-2-quinolinecarboxylic acid;CPD2809-SM;(3S)-3-MethyL;(S)-4-N-BOC-2-METHYL;Sotorasib Impurity 2

CBNumber:: CB9458934

Molecular Formula:: C10H20N2O2

Molecular Weight:: 200.28

MDL Number:: MFCD02683204

MOL File:: 147081-29-6.mol

MSDS File:: SDS

Last updated:2024-04-15 15:30:59

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(S)-1-Boc-3-methylpiperazine Properties

Melting point	40-45 °C
alpha	-16 º (c=1 in dioxane)
Boiling point	268.7±15.0 °C(Predicted)
Density	0.997±0.06 g/cm3(Predicted)
storage temp.	Keep in dark place,Inert atmosphere,2-8°C
pka	8.52±0.40(Predicted)
form	Crystalline Powder
color	White to yellow
optical activity	[α]/D -16±2°, c = 1 in dioxane
Sensitive	Air Sensitive
InChI	InChI=1S/C10H20N2O2/c1-8-7-12(6-5-11-8)9(13)14-10(2,3)4/h8,11H,5-7H2,1-4H3/t8-/m0/s1
InChIKey	FMLPQHJYUZTHQS-QMMMGPOBSA-N
SMILES	N1(C(OC(C)(C)C)=O)CCN[C@@H](C)C1
CAS DataBase Reference	147081-29-6(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS05,GHS07

Signal word

Danger

Hazard statements

H315-H318-H335

Precautionary statements

P280-P302+P352-P305+P351+P338+P310

Hazard Codes

Risk Statements

37/38-41-34

Safety Statements

26-39-45-36/37/39

RIDADR

3259

WGK Germany

10-34

HS Code

29335990

NFPA 704

	1
3		1

(S)-1-Boc-3-methylpiperazine price More Price(55)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	63207	(S)-1-Boc-3-methylpiperazine ≥98%	147081-29-6	1g	$21.9	2024-03-01	Buy
Sigma-Aldrich	63207	(S)-1-Boc-3-methylpiperazine ≥98%	147081-29-6	5G	$65.4	2024-03-01	Buy
Alfa Aesar	H27534	(S)-(-)-1-Boc-3-methylpiperazine, 98%	147081-29-6	1g	$64.65	2024-03-01	Buy
Alfa Aesar	H27534	(S)-(-)-1-Boc-3-methylpiperazine, 98%	147081-29-6	5g	$256	2024-03-01	Buy
TRC	B656830	(S)-4-Boc-2-methylpiperazine	147081-29-6	25g	$305	2021-12-16	Buy

Product number	Packaging	Price	Buy
63207	1g	$21.9	Buy
63207	5G	$65.4	Buy
H27534	1g	$64.65	Buy
H27534	5g	$256	Buy
B656830	25g	$305	Buy

(S)-1-Boc-3-methylpiperazine Chemical Properties,Uses,Production

Description

(S)-1-Boc-3-methylpiperazine is a hydrophobic compound that is structurally modified from the tetracyclic family of drugs. It has been shown to inhibit tumor cell growth by binding to the oncogene, KRASG12C, and downregulating its expression. This compound also inhibits cancer cell growth through the inhibition of the PI3K/AKT signaling pathway. The pharmacological effects of (S)-1-Boc-3-methylpiperazine are dependent on its ability to bind with high affinity to KRASG12C and inhibit its activity.

Chemical Properties

colorless to yellow liquid

Uses

Reactant involved in the synthesis of biologically activy molecules including:

CCR5 antagonists with anti-HIV-1 activity
Opioid receptor antagonists
Human growth hormone secretagogue receptor antagonists for treatment of obesity
Fatty acid oxidation inhibitors

Uses

(S)-4-Boc-2-methylpiperazine ((S)-1-Boc-3-methylpiperazine) is a reagent used in the synthesis of benzamide peptidomimetic as non-ATP competitive inihbitors.

Uses

Laboratory chemicals, Manufacture of substances.

(S)-1-Boc-3-methylpiperazine synthesis

Synthesis of (S)-1-Boc-3-methylpiperazine from (S)-(+)-2-Methylpiperazine

(S)-1-Boc-3-methylpiperazine Preparation Products And Raw materials

Raw materials

Preparation Products

UCB9608

(S)-1-Boc-3-methylpiperazine Suppliers

Global( 342)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Shanghai Boc Chemical Co., Ltd.	021-34975602; +8618721111801	shangli@bocchem.com	China	138	58
AstaTech(Chengdu) Biopharmaceutical Corp.	+86-02882666559 +86-15884417729	gjpu@astatech.com.cn	China	308	58
Golden Pharma Co., Limited	+undefined18958062155	sales@zjgoldpharm.com	China	5905	58
Changzhou AniKare Pharmatech Co., Ltd.	+86-0519-8359-8696 +8618018249389	sales@anikare.com	China	8382	58
Shanghai UCHEM Inc.	+862156762820 +86-13564624040	sales@myuchem.com	China	6710	58
Henan Fengda Chemical Co., Ltd	+86-371-86557731 +86-13613820652	info@fdachem.com	China	8095	58
Capot Chemical Co.,Ltd.	571-85586718 +8613336195806	sales@capotchem.com	China	29797	60
Chembon Pharmaceutical Co., Ltd.	+86-28-8425-2981		CHINA	724	55
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32480	60
Shenzhen Nexconn Pharmatechs Ltd	+86-755-89396905 +86-15013857715	admin@nexconn.com	China	10248	58

Supplier	Advantage
Shanghai Boc Chemical Co., Ltd.	58
AstaTech(Chengdu) Biopharmaceutical Corp.	58
Golden Pharma Co., Limited	58
Changzhou AniKare Pharmatech Co., Ltd.	58
Shanghai UCHEM Inc.	58
Henan Fengda Chemical Co., Ltd	58
Capot Chemical Co.,Ltd.	60
Chembon Pharmaceutical Co., Ltd.	55
ATK CHEMICAL COMPANY LIMITED	60
Shenzhen Nexconn Pharmatechs Ltd	58

View Lastest Price from (S)-1-Boc-3-methylpiperazine manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2024-04-15	(S)-1-Boc-3-methylpiperazine 147081-29-6	US $5.00-0.10 / KG	1KG	99%	g-kg-tons, free sample is available	Henan Fengda Chemical Co., Ltd
2024-02-23	(S)-4-N-Boc-2-methylpiperazine 147081-29-6	US $37.00-788.00 / g	10g	0.99	25kg	Shanghai UCHEM Inc.
2023-06-26	(S)-4-N-Boc-2-methylpiperazine 147081-29-6	US $150.00 / ASSAYS	10g	>99%	500kg/month	Hebei Mingeng Biotechnology Co., Ltd

(S)-1-Boc-3-methylpiperazine
147081-29-6
US $5.00-0.10 / KG
99%
Henan Fengda Chemical Co., Ltd

(S)-4-N-Boc-2-methylpiperazine
147081-29-6
US $37.00-788.00 / g
0.99
Shanghai UCHEM Inc.

(S)-4-N-Boc-2-methylpiperazine
147081-29-6
US $150.00 / ASSAYS
>99%
Hebei Mingeng Biotechnology Co., Ltd

(S)-1-Boc-3-methylpiperazine Spectrum

(S)-4-N-Boc-2-methylpiperazine(147081-29-6)¹HNMR

147081-29-6((S)-1-Boc-3-methylpiperazine)Related Search:

(S)-1-Boc-3-benzylpiperazine (S)-tert-butyl 3-formylpiperidine-1-carboxylate (3S)-3-AMinoazepane-1-carboxylic Acid tert-Butyl Ester (S)-1-N-Boc-3-ethylpiperazine (S)-1-BOC-3-PROPYLPIPERAZINE

R-N-4-Boc-N-1-Cbz-2-piperazine carboxylic acid N-4-Boc-2-piperazinecarboxylic acid (S)-1-Boc-3-methylpiperazine 1-BOC-3,5-DIMETHYL-PIPERAZINE t-Butyl(2R,5S)-2,5-dimethylpiperazine-1-carboxylate

(R)-4-N-Boc-piperazine-2-carboxylic acid methyl ester (R)-1-BOC-3-(Hydroxymethyl)piperazine (S)-2-tert-Butylcarboxamide-4-tert-butoxycarbonyl piperazine (1S,4S)-2-BOC-2,5-DIAZABICYCLO[2.2.1]HEPTANE (S)-1-N-Boc-2-methylpiperazine

4-N-Boc-2-Methyl-piperazine 1-Boc-2-Methylpiperazine (R)-1-Boc-3-methylpiperazine

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TERT-BUTYL (S)-3-METHYL-1-PIPERAZINECARBOXYLATE (S)-N4-BOC-2-METHYLPIPERAZINE (S)-1-TERT-BUTOXYCARBONYL-3-METHYLPIPERAZINE (S)-1-N-BOC-3-METHYLPIPERAZINE (S)-3-METHYL-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER (S)-4-N-BOC-2-METHYL PIPERAZINE 1-PIPERAZINECARBOXYLIC ACID, 3-METHYL-, 1,1-DIMETHYLETHYL ESTER, (3S)- (S)-1-Boc-3-methylpiperazine≥ 99% (HPLC, Chiral purity) 4-BOC-2-(S)-METHYL-PIPERAZINE (3S)-1-BOC-3-METHYLPIPERAZINE (S)-3-Methyl-1-Boc-piperazine (S)-4-N-Boc-2-MethylPiperazinee (S)-4-N-Boc-2-methylpiperazine (S)-4-N-Boc-2-methyl piperazine (S)-2-METHYL-1-BOC-PIPERAZINE (S)-2-Methylpiperazine, N4-BOC protected (S)-3-Methylpiperazine, N1-BOC protected (S)-4-N-BOC-2-METHYL (s)-3-methyl-piperazine-1-carboxylic acid tert-butyl (S)-4-N-BOC-2-Methylpiperazine-HCl (3S)-3-Methylpiperazine-1-carboxylic acid tert-butyl ester tert-Butyl (3S)-3-methylpiperazine-1-carboxylate, (3S)-1-(tert-Butoxycarbonyl)-3-methylpiperazine (S)-1-Boc-3-Methylpiperazine (S)-1-Boc-3-Methylpiperazine, 98%+ (3S)-3-Methylpiperazine, N1-BOC protected Chemdraw8(S)-3-Methyl-piperazine-1-carboxylic acid tert-butyl ester CPD2809-SM (3S)-3-MethyL (S)-4-N-Boc-2-methylpiperazine ISO 9001：2015 REACH (S)-TERT-BUTYL 3-METHYLPIPERAZINE-1-CARBOXYLATE (S)-1-BOC-3-METHYLPIPERAZINE tert-butyl (S)-3-methylpiperazine-1-carboxylate 4-HYDROXY-7-METHOXYQUINOLINE-2-CARBOXYLIC ACID (S)-4-Boc-2-methylpiperazine 4-Hydroxy-7-methoxy-2-quinolinecarboxylic acid 1-Piperazinecarboxylic acid, 3-methyl-, 1,1-dimethylethyl ester, (3S)- (9CI, ACI) 3-methyl-1-Piperazinecarboxylic acid 1,1-dimethylethyl ester (3S)- (9CI ACI) 3-Methyl-1-piperazinecarboxylic acid tert-butyl ester (3S)- Sotorasib Impurity 2 147081-29-6 Asymmetric Synthesis Chiral Building Blocks Heterocyclic Building Blocks Piperazines Piperazines pharmacetical Piperazine series Quinoline series Piperaizine 147081-29-6