달포프리스틴

달포프리스틴
달포프리스틴 구조식 이미지
카스 번호:
112362-50-2
한글명:
달포프리스틴
동의어(한글):
달포프리스틴
상품명:
Dalfopristin
동의어(영문):
RP 54476;Dalfopristin;Dalfopristin Mesylate;RP-54476,RP 54476,Inhibitor,Dalfopristin,Antibiotic,Bacterial,inhibit;(3R,4R,5E,10E,12E,14S,26R,26aS)-26-[[2-(Diethylamino)ethyl]sulfonyl]-8,9,14,15,24,25,26,26a-octahydro-14-hydroxy-4,12-dimethyl-3-(1-methylethyl)-3H-21,18-nitrilo-1H,22H-pyrrolo[2,1-c][1,8,4,19]dioxadi;(3R,4R,5E,10E,12E,14S,26R,26aS)-26-[[2-(DiethylaMino)ethyl]sulfonyl]-8,9,14,15,24,25,26,26a-octahydro-14-hydroxy-4,12-diMethyl-3-(1-Methylethyl)-3H-21,18-nitrilo-1H,22H-pyrrolo[2,1-c][1,8,4,19]dioxadiazacyclotetracosine-1,7,16,22(4H,17H)-tetr;(3R,4R,5E,10E,12E,14S,26R,26aS)-26-[[2-(Diethylamino)ethyl]sulfonyl]-8,9,14,15,24,25,26,26a-octahydro-14-hydroxy-4,12-dimethyl-3-(1-methylethyl)-3H-21,18-nitrilo-1H,22H-pyrrolo[2,1-c][1,8,4,19]dioxadiazacyclotetracosine-1,7,16,22(4H,17H)-tetrone;3H-21,18-Nitrilo-1H,22H-pyrrolo[2,1-c][1,8,4,19]dioxadiazacyclotetracosine-1,7,16,22(4H,17H)-tetrone, 26-[[2-(diethylamino)ethyl]sulfonyl]-8,9,14,15,24,25,26,26a-octahydro-14-hydroxy-4,12-dimethyl-3-(1-methylethyl)-, (3R,4R,5E,10E,12E,14S,26R,26aS)-
CBNumber:
CB31075198
분자식:
C34H50N4O9S
포뮬러 무게:
690.85
MOL 파일:
112362-50-2.mol

달포프리스틴 속성

녹는점
~150°
끓는 점
940.5±65.0 °C(Predicted)
밀도
1.27±0.1 g/cm3(Predicted)
저장 조건
Store at -20°C
용해도
DMSO:113.0(Max Conc. mg/mL);163.57(Max Conc. mM)
Ethanol:100.0(Max Conc. mg/mL);144.75(Max Conc. mM)
산도 계수 (pKa)
13.18±0.70(Predicted)

안전

유해 물질 데이터 112362-50-2(Hazardous Substances Data)

달포프리스틴 C화학적 특성, 용도, 생산

용도

Dalfopristin is a semi-synthetic analogue of ostreogyrcin A (virginiamycin M, pristinamycin IIA, streptogramin A) formed by addition of diethylaminoethylthiol to the 2-pyrroline group of ostreogyrcin, followed by oxidation to the sulphone. The structural changes provide a more hydrophobic compound with a readily ionisable group for generating a salt. Dalfopristin is used commercially in synergistic combination with quinupristin (70:30). There is little published data on the synthesis, biological or antibiotic activity of dalfopristin alone, however the combination product is highly effective, including activity against antibiotic resistant strains.

달포프리스틴 준비 용품 및 원자재

원자재

준비 용품


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