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Brinzolamide-d5

Brinzolamide-d5 구조식 이미지

카스 번호:: 1217651-02-9

상품명:: Brinzolamide-d5

동의어(영문):: Brinzolamide-d5;[2H5]-Brinzolamide

CBNumber:: CB32507883

분자식:: C12H21N3O5S3

포뮬러 무게:: 383.5

MOL 파일:: 1217651-02-9.mol

속성

안전

용도

공급 업체 20

Brinzolamide-d5 속성

저장 조건: Refrigerator

용해도: 에 용해됨에탄올

물리적 상태: 고체

물리적 상태: 단단한 모양

색상: 수정 같은

안전

위험 및 안전 성명

그림문자(GHS):

신호 어:

Warning

유해·위험 문구:

암호	유해·위험 문구	위험 등급	범주	신호 어	그림 문자	P- 코드

예방조치문구:

NFPA 704

	0
2		0

Brinzolamide-d5 C화학적 특성, 용도, 생산

개요

Brinzolamide-d₅ is intended for use as an internal standard for the quantification of brinzolamide by GC- or LC-MS. Brinzolamide is a potent inhibitor of carbonic anhydrase II (CAII) and CAIV (IC₅₀s = 3.19 and 45.3 nM, respectively). It is selective for CAII and CAIV over CAI (IC₅₀ = ~1,365 nM). Brinzolamide (30 mg/kg) reduces intestinal charcoal meal progression by 44% and prolongs pentobarbital sodium-induced sleep time by 35% in mice. Topical administration of brinzolamide (0.25, 0.5, and 1 mg/eye) reduces intraocular pressure in a rabbit model of spontaneous ocular hypertension. It also reduces intraocular pressure in a cynomolgus monkey model of argon laser trabeculoplasty-induced ocular hypertension. Formulations containing brinzolamide have been used in the treatment of glaucoma and ocular hypertension.

화학적 성질

Crystalline Solid

용도

Carbonic anhydrase inhibitor. Antiglaucoma agent.

Brinzolamide-d5 준비 용품 및 원자재

원자재

준비 용품

Brinzolamide-d5 공급 업체

글로벌( 20)공급 업체

공급자	전화	이메일	국가	제품 수	이점
Chemsky（shanghai）International Co.,Ltd.	021-50135380	shchemsky@sina.com	China	32344	50
Shanghai EFE Biological Technology Co., Ltd.	021-65675885 18964387627	info@efebio.com	China	9709	58
Hubei Yangxin Medical Technology Co., Ltd.	15374522761	3003392093@qq.com	China	7934	55
Shanghai Hongye Biotechnology Co. Ltd	400-9205774	sales@glpbio.cn	China	6870	58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	18818260767	sales@chemegen.com	China	11289	58
Energy Chemical	021-58432009 400-005-6266	marketing1@energy-chemical.com	China	44894	58
Shanghai isotope chemical co.,ltd	021-021-51600108 13062666369	sales@chinaisotope.com	China	4272	58
Nanjing Shizhou Biology Technology Co.,Ltd	17301488900	judy.xia@synzest.com	China	12584	58

Brinzolamide-d5 관련 검색:

N-DESMETHYLDILTIAZEM, HYDROCHLORIDE DESACETYL DILTIAZEM HCL N-Desethyl Brinzolamide Diltiazem-d6 Diltiazem N-Oxide Brinzolamide Diltiazem Impurity 5 BrinzolaMide iMpurity Diltiazem impurity (S)-3,4-Dihydro-4-hydroxy-2-(3-methoxypropyl)-2H-thieno[3,2-e]-1,2-thiazine-6-sulfonamide 1,1-dioxide Diltiazem Impurity 4 Diltiazem hydrochloride Deacetyl Diltiazem N-Oxide N,N,O-Tridesmethyl Diltiazem Deacetyldiltiazem (2R-cis)-3-acetoxy-5-[2-(dimethylamino)ethyl]-2,3-dihydro-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one monohydrochloride Diltiazem Impurity 8 Diltiazem Impurity 3