ChemicalBook >제품 카탈로그 >1,2,3-벤젠트리올,4-[[[2-(사이클로헥실리미노)-4-

1,2,3-벤젠트리올,4-[[[2-(사이클로헥실리미노)-4-

1,2,3-벤젠트리올,4-[[[2-(사이클로헥실리미노)-4- 구조식 이미지

카스 번호:: 509102-00-5

한글명:: 1,2,3-벤젠트리올,4-[[[2-(사이클로헥실리미노)-4-

동의어(한글):: 1,2,3-벤젠트리올,4-[[[2-(사이클로헥실리미노)-4-

상품명:: 1,2,3-Benzenetriol, 4-[[[2-(cyclohexyliMino)-4-

동의어(영문):: MIM1;CS-1192;MIM 1;MIM-1;Inhibitor of Mcl-1;1,2,3-Benzenetriol, 4-[[[2-(cyclohexyliMino)-4-;4-[[[2-(Cyclohexylimino)-4-methyl-3(2H)-thiazolyl]imino]methyl]-1,2,3-benzenetriol;inhibit,Bcl-2 Family,Inhibitor of Mcl1,Inhibitor,MIM-1,MIM1,MIM 1,Inhibitor of Mcl 1;1,2,3-Benzenetriol, 4-[[[2-(cyclohexylimino)-4-methyl-3(2H)-thiazolyl]imino]methyl]-

CBNumber:: CB32652150

분자식:: C17H21N3O3S

포뮬러 무게:: 347.43

MOL 파일:: 509102-00-5.mol

속성

안전

용도

공급 업체 53

1,2,3-벤젠트리올,4-[[[2-(사이클로헥실리미노)-4- 속성

끓는 점: 559.6±60.0 °C(Predicted)

밀도: 1.40±0.1 g/cm3(Predicted)

용해도: insoluble in EtOH; insoluble in H2O; ≥12.15 mg/mL in DMSO

물리적 상태: 결정성 고체

산도 계수 (pKa): 7.73±0.45(Predicted)

안전

1,2,3-벤젠트리올,4-[[[2-(사이클로헥실리미노)-4- C화학적 특성, 용도, 생산

개요

MIM1 is an inhibitor of Mcl-1, an antiapoptotic Bcl-2 family protein with a role in cancer. It selectively engages the canonical groove of Mcl-1, inhibiting its ability to bind BH3 domains (IC₅₀ = 4.7 μM). MIM1 induces caspase-3/7 activation and cell death in Mcl-1-dependent leukemia cells.

용도

MIM1 binds to MCL-1 and aids in the modulation of cell death, division and differentiation. MIM1 may be used for treating hyperproliferative disorders, angiogenesis disorders, cell cycle regulation disorders, autophagy regulation disorders, inflammatory disorders, and/or infectious disorders.

1,2,3-벤젠트리올,4-[[[2-(사이클로헥실리미노)-4- 준비 용품 및 원자재

원자재

준비 용품

1,2,3-벤젠트리올,4-[[[2-(사이클로헥실리미노)-4- 공급 업체

글로벌( 53)공급 업체

공급자	전화	이메일	국가	제품 수	이점
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32715	60
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
Career Henan Chemica Co	+86-0371-86658258 15093356674;	laboratory@coreychem.com	China	30255	58
Hangzhou MolCore BioPharmatech Co.,Ltd.	+86-057181025280; +8617767106207	sales@molcore.com	China	49739	58
Aladdin Scientific	+1-+1(833)-552-7181	sales@aladdinsci.com	United States	52927	58
Amadis Chemical Company Limited	571-89925085	sales@amadischem.com	China	131980	58
MedChemexpress LLC	021-58955995	sales@medchemexpress.cn	United States	4863	58
EMMX Biotechnology LLC	888-539-0666	info@emmx.com	United States	8449	60
Pharmacodia (Beijing) Co.,Ltd	+86-400-851-9921	sales@pharmacodia.com	China	2317	55
Shanghai EFE Biological Technology Co., Ltd.	021-65675885 18964387627	info@efebio.com	China	9709	58

1,2,3-벤젠트리올,4-[[[2-(사이클로헥실리미노)-4- 관련 검색:

Methylcyclohexane