벤조말빈A

벤조말빈A
벤조말빈A 구조식 이미지
카스 번호:
157047-96-6
한글명:
벤조말빈A
동의어(한글):
벤조말빈A
상품명:
benzomalvin A
동의어(영문):
benzomalvin A;Quinazolino[3,2-a][1,4]benzodiazepine-5,13-dione, 6,7-dihydro-6-methyl-7-(phenylmethyl)-, (6S,7S)-
CBNumber:
CB51347114
분자식:
C24H19N3O2
포뮬러 무게:
381.43
MOL 파일:
157047-96-6.mol

벤조말빈A 속성

끓는 점
599.3±60.0 °C(Predicted)
밀도
1.28±0.1 g/cm3(Predicted)
저장 조건
Store at -20°C
용해도
DMF: Soluble; DMSO: Soluble; Ethanol: Soluble; Methanol: Soluble
물리적 상태
고체
산도 계수 (pKa)
-0.46±0.40(Predicted)

안전

벤조말빈A C화학적 특성, 용도, 생산

개요

Benzomalvin A is a fungal metabolite produced by Penicillium. It inhibits yeast α-glucosidase in vitro (IC50 = 383.2 μM). In vivo, benzomalvin A (3.1-31.6 mg/kg) decreases plasma glucose levels in mice following administration of sucrose. It also decreases the plasma glucose postprandial peak in nicotinamide-streptozotocin-induced hyperglycemic mice when administered at a dose of 10 mg/kg. Benzomalvin A also acts as an antagonist of neurokinin-1 (NK1) receptors, inhibiting binding of substance P to guinea pig, rat, and human NK1 (Kis = 12, 42, and 43 μM, respectively).

벤조말빈A 준비 용품 및 원자재

원자재

준비 용품


벤조말빈A 공급 업체

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