4-히드록시인돌
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4-히드록시인돌 속성
- 녹는점
- 97-99 °C(lit.)
- 끓는 점
- 245.66°C (rough estimate)
- 밀도
- 1.1475 (rough estimate)
- 증기압
- 0.019Pa at 25℃
- 굴절률
- 1.5260 (estimate)
- 저장 조건
- 0-6°C
- 용해도
- DMSO(약간 용해됨), 메탄올(약간 용해됨)
- 물리적 상태
- 고체
- 물리적 상태
- 단단한 모양
- 산도 계수 (pKa)
- 9.89±0.40(Predicted)
- 색상
- 진한 노란색에서 녹색 회색까지
- 수용성
- 약간 용해됨
- 감도
- Air Sensitive
- BRN
- 114905
- InChIKey
- NLMQHXUGJIAKTH-UHFFFAOYSA-N
- LogP
- 1.57 at 25℃
- CAS 데이터베이스
- 2380-94-1(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
| 위험품 표기 | Xi | ||
|---|---|---|---|
| 위험 카페고리 넘버 | 36/37/38 | ||
| 안전지침서 | 26-36-37/39 | ||
| WGK 독일 | 3 | ||
| 위험 참고 사항 | Irritant | ||
| 위험 등급 | IRRITANT, KEEP COLD | ||
| HS 번호 | 29339900 |
4-히드록시인돌 C화학적 특성, 용도, 생산
화학적 성질
Off-White Cyrstalline Solid용도
4-Hydroxyindole is a Pindolol (P468000) impurity, which is a mixed adrenergic blocker and serotonin 5HT1A-receptor antagonist.정의
ChEBI: 4-hydroxyindole is a member of the class of hydroxyindoles that is 1H-indole substituted by a hydroxy group at position 4. It is a member of phenols and a member of hydroxyindoles.주요 응용
4-Hydroxyindole as simple indoles is the important raw material or intermediate in the synthesis of pharmaceutical products and industrial polymers. It effectively inhibits Abeta peptide-induced amyloid fibril formation and prevent cell death induced by the peptide in culture. It is used for the synthesis of anti-inflammatory angular pyrrolocoumarins.제조 방법
Synthesis of 4-hydroxyindole: Using resorcinol as raw material, 4-oxotetrahydrocoumarone carboxylic acid is prepared by isomerization, catalytic hydrogenation, and cyclization with ethyl bromopyruvate. It was added to methanol solution saturated with ammonia, and the reaction was heated in an autoclave to generate 4-oxotetrahydroindole. Finally, 4-hydroxyindole is obtained by dehydrogenation and isomerization.일반 설명
Glucouridination of 4-hydroxyindole by human uridine 5′-diphospho-glucuronosyltransferase has been repotrted.4-히드록시인돌 준비 용품 및 원자재
원자재
준비 용품
4-히드록시인돌 공급 업체
글로벌( 554)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Suzhou Chukai Pharma Tech Co.,Ltd | +8615062531973 |
2279973922@qq.com | China | 224 | 58 |
| Junwee Chemical co., Ltd. | +86-571-85808636 +86-13958122542 |
sales@junweechem.com | China | 821 | 58 |
| Qingdao Dexin Chemical Co., Ltd | +8615553333686 |
15553333686@qq.com | China | 926 | 58 |
| Hebei Yanxi Chemical Co., Ltd. | +8617531190177 |
peter@yan-xi.com | China | 5993 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 |
info@fdachem.com | China | 7934 | 58 |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 |
sales@capotchem.com | China | 29797 | 60 |
| Beijing Cooperate Pharmaceutical Co.,Ltd | 010-60279497 |
sales01@cooperate-pharm.com | CHINA | 1811 | 55 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21691 | 55 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 |
ivan@atkchemical.com | China | 32480 | 60 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418679 +86-18949832763 |
info@tnjchem.com | China | 2989 | 55 |
4-히드록시인돌 관련 검색:
핀도롤 비스(1,2,2,6,6,-펜타메틸-4-피페리딜)데탄디온산 비스(4-아미노페닐) 에테르 3-인돌부틸산 인돌-3-아세트산 인드메타신 6-히드록시인돌 5-히드록시인돌 5-히드록시인돌-2-카르복시산 4-히드록시인돌
Protocatechuic acid
2-Methylcyclohexylamine
1-Chloro-3-(1H-indol-4-yloxy)-2-propanol
3-HYDROXYINDOLE
PSILOCIN
4-Methoxyindole
4-Benzyloxyindole-3-carboxaldehyde
METHYL 4-METHOXY-2-INDOLECARBOXYLATE