1-(4,4-디페닐-3-부테닐)-3-피페리딘카복실산염산염

1-(4,4-디페닐-3-부테닐)-3-피페리딘카복실산염산염
1-(4,4-디페닐-3-부테닐)-3-피페리딘카복실산염산염 구조식 이미지
카스 번호:
85375-15-1
한글명:
1-(4,4-디페닐-3-부테닐)-3-피페리딘카복실산염산염
동의어(한글):
1-(4,4-디페닐-3-부테닐)-3-피페리딘카복실산염산염
상품명:
1-(4,4-DIPHENYL-3-BUTENYL)-3-PIPERIDINECARBOXYLIC ACID HYDROCHLORIDE
동의어(영문):
skf-89976a;SKF89976AHCl;SKF 89976A HYDROCHLORIDE;l-SKF89976A hydrochloride;d,l-SKF89976A hydrochloride;1-(4,4-DIPHENYL-3-BUTENYL)-3-PIPERIDINECARBOXYLIC ACID HYDROCHLORIDE;1-(4,4-Diphenylbut-3-en-1-yl)piperidine-3-carboxylic acid hydrochloride;1-(4,4-Diphenyl-3-buten-1-yl)-3-piperidinecarboxylic acid hydrochloride;Gamma-aminobutyric acid Receptor,γ-Aminobutyric acid Receptor,d,l-SKF89976A,GABA Receptor,SKF89976A,inhibit,SKF89976A hydrochloride,Inhibitor,SKF-89976A hydrochloride
CBNumber:
CB7194179
분자식:
C22H26ClNO2
포뮬러 무게:
371.9
MOL 파일:
85375-15-1.mol

1-(4,4-디페닐-3-부테닐)-3-피페리딘카복실산염산염 속성

저장 조건
Inert atmosphere,2-8°C
용해도
DMSO: 20mg/mL, 가용성
물리적 상태
고체
물리적 상태
단단한 모양
색상
하얀색

안전

WGK 독일 3
RTECS 번호 TM6241000

1-(4,4-디페닐-3-부테닐)-3-피페리딘카복실산염산염 C화학적 특성, 용도, 생산

용도

SKF-89976A is a GABA transporters (GATs) type 1 inhibitor.

생물학적 활성

A potent GABA uptake inhibitor, selective for GAT-1 (IC 50 values are 0.13, 550, 944 and 7210 μ M for hGAT-1, rGAT-2, hGAT-3 and hBGT-1 respectively). Inhibits transport current competitively (K i = 7 μ M) and transmitter-gated current non-competitively (K i = 0.03 nM). Able to pass the blood-brain barrier after systemic administration and is active in vivo .

1-(4,4-디페닐-3-부테닐)-3-피페리딘카복실산염산염 준비 용품 및 원자재

원자재

준비 용품


1-(4,4-디페닐-3-부테닐)-3-피페리딘카복실산염산염 공급 업체

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