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Rosiglitazone maleate

Rosiglitazone maleate Suppliers list
Company Name: Mainchem Co., Ltd.
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Products Intro: Product Name:Rosiglitazone maleate
CAS:155141-29-0
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Products Intro:Product Name:Rosiglitazone Maleate
CAS:155141-29-0
Package:250Mg,25Mg
Company Name: TAIYUAN RHF CO.,LTD.  
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Products Intro:Product Name:Rosiglitazone Maleate
CAS:155141-29-0
Purity:98%;99% Package:1g;5g;25g;100g;250g;500g;1kg
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Products Intro:CAS:155141-29-0
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Products Intro:Product Name:Rosiglitazone Maleate
CAS:155141-29-0
Purity:99% Package:100Mg;1g;5g
Rosiglitazone maleate Basic information
Product Name:Rosiglitazone maleate
Synonyms:5-((4-[2-(METHYL-2-PYRIDINYLAMINO)-ETHOXY]-PHENYL)-METHYLENE)-2,4-THIAZOLIDINEDIONE;5-{p-[2-(methyl-2-pyridylamino)ethoxy]benzyl}-2,4-thiazolidinedione maleate;ROSIGLITAZONE MALEATE;RosiglitazoneTartrate;Avandi;BRL-49653c;RSIGLITAZONEMALEATE;5-(4-(2-(Methyl(pyridin-2-yl)aMino)ethoxy)benzyl)thiazolidine-2,4-dione Maleate
CAS:155141-29-0
MF:C22H23N3O7S
MW:473.5
EINECS:1312995-182-4
Product Categories:Active Pharmaceutical Ingredients;Antidiabetic;Intermediates & Fine Chemicals;Pharmaceuticals;API's;Rosiglitazone;Heterocycles;Sulfur & Selenium Compounds;Inhibitor;API
Mol File:155141-29-0.mol
Rosiglitazone maleate Structure
Rosiglitazone maleate Chemical Properties
Melting point 235-240°C
storage temp. -20°C Freezer
pka6.1; 6.8(at 25℃)
CAS DataBase Reference155141-29-0(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
Risk Statements 20/21/22-36/38
Safety Statements 24/25-37/39-26
MSDS Information
Rosiglitazone maleate Usage And Synthesis
Chemical PropertiesWhite To Off-White Solid
UsesInsulin sensitizer; binds to peroxisome proliferator activated receptor gamma (PPAR- γ).
UsesThiazole alkanes antidiabetic drug
UsesThiazolidinediones (TZDs) are a group of structurally related peroxisome proliferator-activated receptor γ (PPARγ) agonists with antidiabetic actions in vivo. Rosiglitazone is a prototypical TZD that has served as a reference compound for this class. It is a potent and selective PPARγ ligand that binds to the PPARγ ligand-binding domain with a Kd value of 43 nM. It activates luciferase-based expression constructs PPARγ1 and PPARγ2 with EC50 values of approximately 30 nM and 100 nM, respectively. Rosiglitazone is active in vivo as an antidiabetic agent in the ob/ob mouse model, and has been used as an oral hypoglycemic agent in the treatment of type 2 diabetes in humans for many years.[Cayman Chemical]
Rosiglitazone maleate Preparation Products And Raw materials
Tag:Rosiglitazone maleate(155141-29-0) Related Product Information
Rosiglitazone maleate Enalapril maleate Cinepazide maleate Benzyl isocyanate 2,4-Thiazolidinedione Ethoxyquin Ethoxyethyne Ethoxyamine hydrochloride Benzyl TRIS MALEATE Ethoxy Rosiglitazone Benzyl chloride Benzyl benzoate Benzyl alcohol DIETHOXYMETHANE Rosiglitazone hydrochloride Ethoxymethylenemalononitrile