- Amezinium Methyl Sulfate
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- $15.00 / 1KG
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2021-07-02
- CAS:30578-37-1
- Min. Order: 1KG
- Purity: 99%+ HPLC
- Supply Ability: Monthly supply of 1 ton
- Amezinium methylsulfate
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- $1.00 / 1KG
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2019-09-03
- CAS:30578-37-1
- Min. Order: 1KG
- Purity: 95.0-99.8%
- Supply Ability: 1KG;5KG 10KG; 100KG
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| | Amezinium methylsulfate Basic information |
| Product Name: | Amezinium methylsulfate | | Synonyms: | 6-methoxy-1-phenylpyridazin-1-ium-4-amine methylsulfate;SUPRATONIN (GRUNENTHAL);RISUMIC (DAINIPPON);REGULTON (KNOLL);AMEZINIUM METHYL SULFATE;4-amino-6-methoxy-1-phenyl-pyridaziniumethylsulfate;Supratonin;Tenfortan | | CAS: | 30578-37-1 | | MF: | C12H15N3O5S | | MW: | 313.33 | | EINECS: | 250-248-0 | | Product Categories: | | | Mol File: | 30578-37-1.mol |  |
| | Amezinium methylsulfate Chemical Properties |
| Melting point | 176° (dec) | | storage temp. | Inert atmosphere,Room Temperature | | solubility | DMSO : ≥ 34 mg/mL (108.51 mM) | | form | powder to crystal | | color | White to Light yellow | | Merck | 14,394 | | CAS DataBase Reference | 30578-37-1 |
| RTECS | UR6066500 | | HS Code | 2933.59.8000 | | Toxicity | LD50 in mice, rats (mg/kg): 1630, 1410 orally; 40.4, 45.5 i.v. (Teschendorf) |
| | Amezinium methylsulfate Usage And Synthesis |
| Originator | Regulton,Nordmark,W. Germany,1981 | | Definition | ChEBI: Amezinium metilsulfate is an azaheterocycle sulfate salt of amezinium. It is a sympathomimetic drug which suppresses noradrenaline reuptake and thereby elevating blood pressure. It is used for the treatment of low blood pressure in patients undergoing dialysis. It has a role as an EC 1.4.3.4 (monoamine oxidase) inhibitor, an antihypotensive agent, a sympathomimetic agent and an adrenergic uptake inhibitor. It contains an amezinium. | | Manufacturing Process | 18.7 parts of 1-phenyl-4-aminopyridazone-(6) and 19 parts of dimethyl
sulfate in 400 parts of xylene are kept at 120°C for one hour while mixing
well. The reaction mixture is suction filtered, 28 parts (89.5% of the theory)
of 1-phenyl-4-amino-6-methoxypyridazinium methosulfate is obtained having
a melting point of 173°C to 174°C after recrystallization from acetonitrile. The
perchlorate has a melting point of 179°C to 182°C. | | Therapeutic Function | Antihypotensive |
| | Amezinium methylsulfate Preparation Products And Raw materials |
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