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| | 2-Chloroethyl chloroformate Basic information |
| Product Name: | 2-Chloroethyl chloroformate | | Synonyms: | 2-chlorethylesterkyselinychlormravenci(czech);2-Chloroethyl chloridocarbonate;2-Chloroethyl chlorocarbonate;beta-chloroethylchlorocarbonate;Carbonochloridicacid,2-chloroethylester;Carbonochloridicacid2-chloroethylester;chlorocarbonicacid2-chloro-ethylester;Chloroformic acid beta-chloroethyl ester | | CAS: | 627-11-2 | | MF: | C3H4Cl2O2 | | MW: | 142.97 | | EINECS: | 210-982-4 | | Product Categories: | Agrochemicals;CHLOROFORMATES | | Mol File: | 627-11-2.mol |  |
| | 2-Chloroethyl chloroformate Chemical Properties |
| | 2-Chloroethyl chloroformate Usage And Synthesis |
| Chemical Properties | Clear colorless liquid | | Uses | 2-Chloroethyl Chloroformate is a reactant used in the preparation of artemisinin-derived dimer carbonates and thiocarbonates with antimalarial activity. | | General Description | Liquid. | | Air & Water Reactions | Decomposed slowly by water forming ethanol, HCl, and CO2; on contact with moist air, 2-Chloroethyl chloroformate gives off HCl fumes; attacks many metals especially in humid atmosphere. REF [Handling Chemicals Safely, 1980. p. 476]. | | Reactivity Profile | 2-Chloroethyl chloroformate is an acid halide. Acid halides are water reactive; some are violently reactive. They are incompatible with strong oxidizing agents, alcohols, amines, alkali. May react vigorously or explosively if mixed with diisopropyl ether or other ethers in the presence of trace amounts of metal salts [J. Haz. Mat., 1981, 4, 291]. | | Health Hazard | (Non-Specific -- Ethyl Chloroformate) Poisonous; may be fatal if inhaled, swallowed or absorbed through skin. Contact may cause burns to skin and eyes. | | Safety Profile | Poison by inhalation.
May also cause fatahties by ingestion or skin
contact. May cause burns to the eyes and
skin. When heated to decomposition it emits
toxic fumes of Cl- | | Purification Methods | Purify it by fractional distillation, preferably in a vacuum and store it in a dry atmosphere. [Jones J Chem Soc 2735 1957, Beilstein 3 IV 24.] |
| | 2-Chloroethyl chloroformate Preparation Products And Raw materials |
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