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| Product Name: | DCEBIO | | Synonyms: | DCEBIO;5,6-DICHLORO-1-ETHYL-1,3-DIHYDRO-2H-BENZIMIDAZOL-2-ONE;5,6-DICHLORO-1-ETHYL-1,3-DIHYDRO-2H-BENZIMIDAZOLE-2-ONE;5,6-DICHLORO-1-ETHYL-1H-BENZO[D]IMIDAZOL-2(3H)-ONE;2H-Benzimidazol-2-one, 5,6-dichloro-1-ethyl-1,3-dihydro-;Potassium Channel,KcsA,DCEBIO,inhibit,Inhibitor | | CAS: | 60563-36-2 | | MF: | C9H8Cl2N2O | | MW: | 231.08 | | EINECS: | | | Product Categories: | Potassium channel | | Mol File: | 60563-36-2.mol |  |
| | DCEBIO Chemical Properties |
| Melting point | 205-207 °C(Solv: ethyl acetate (141-78-6)) | | density | 1.412±0.06 g/cm3(Predicted) | | storage temp. | Store at RT | | solubility | DMSO: >10mg/mL | | form | solid | | pka | 10.28±0.30(Predicted) | | color | off-white |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-36 | | WGK Germany | 3 |
| | DCEBIO Usage And Synthesis |
| Description | DCEBIO, a derivative of 1-EBIO, is an extremely potent activator of Cl- secretion in T84 colonic cells. DCEBIO stimulates Cl- secretion via the activation of hIK1 K+ channels and the activation of an apical membrane Cl- conductance. | | Uses | DCEBIO is a small Ca2+sensitive K+ channel (SKCa) agonist. It also stimulate nitric oxide (NO) synthesis and vasodilation in resistance arteries. | | Definition | ChEBI: DCEBIO is a dichlorobenzene. | | Biological Activity | Stimulates Cl - secretion via activation of hIK1 K + channels and the activation of an apical Cl - conductance. More potent than its analog 1-EBIO (1-Ethyl-2-benzimidazolinone ). | | storage | Store at RT |
| | DCEBIO Preparation Products And Raw materials |
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