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Tris(2-chloroethyl) phosphate

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Products Intro: Product Name:Tris(2-chloroethyl) phosphate
CAS:115-96-8
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CAS:115-96-8
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CAS:115-96-8
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CAS:115-96-8
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Products Intro: Product Name: Tris(2-chloroethyl) phosphate
CAS:115-96-8
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Tris(2-chloroethyl) phosphate manufacturers

Tris(2-chloroethyl) phosphate Basic information
Product Name:Tris(2-chloroethyl) phosphate
Synonyms:Tris2-chloroethyl;PHOSPHORIC ACID TRIS(2-CHLOROETHYL) ESTER;TRICHLOROETHYL PHOSPHATE;Trichlorethyl phosphate;TRI-2-CHLOROETHYL PHOSPHATE;TRIS(BETA-CHLOROETHYL) PHOSPHATE;AURORA KA-1645;2-Chloroethanol phosphate
CAS:115-96-8
MF:C6H12Cl3O4P
MW:285.49
EINECS:204-118-5
Product Categories:Organic Building Blocks;Organic Phosphates/Phosphites;Phosphorus Compounds;organophosphorus compound;Metabolites & Impurities;Organics;Functional Materials;Phosphates (Plasticizer);Plasticizer;Metabolites & Impurities, Phosphorylating and Phosphitylating Agents;Building Blocks;Chemical Synthesis;Organic Building Blocks;Organic Phosphates/Phosphites;Phosphorus Compounds;Phosphorylating and Phosphitylating Agents
Mol File:115-96-8.mol
Tris(2-chloroethyl) phosphate Structure
Tris(2-chloroethyl) phosphate Chemical Properties
Melting point -51 °C
Boiling point 192 °C/10 mmHg (lit.)
density 1.39 g/mL at 25 °C (lit.)
vapor pressure <10 mm Hg ( 25 °C)
refractive index n20/D 1.472(lit.)
Fp 450 °F
storage temp. 2-8°C
solubility H2O: soluble7.82g/L
form Liquid
color Clear colorless
Water Solubility 7 g/L (20 ºC)
Stability:Stable. Incompatible with strong bases, strong oxidizing agents.
InChIKeyHQUQLFOMPYWACS-UHFFFAOYSA-N
LogP1.7 at 20℃
CAS DataBase Reference115-96-8(CAS DataBase Reference)
IARC3 (Vol. 48, 71) 1999
NIST Chemistry ReferencePhosphoric acid, tri-2-chloroethyl ester(115-96-8)
EPA Substance Registry SystemTris(2-chloroethyl) phosphate (115-96-8)
Safety Information
Hazard Codes Xn,N,T
Risk Statements 22-40-51/53-60
Safety Statements 36/37-61-45-53
RIDADR UN 2810 6.1/PG 3
WGK Germany 3
RTECS KK2450000
HazardClass 9
PackingGroup III
HS Code 29199000
Hazardous Substances Data115-96-8(Hazardous Substances Data)
ToxicityLD50 oral in rat: 1230mg/kg
MSDS Information
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Tris(2-chloroethyl) phosphate English
SigmaAldrich English
ACROS English
Tris(2-chloroethyl) phosphate Usage And Synthesis
Chemical PropertiesClear, transparent liquid. Slightly water soluble. Combustible.
UsesA human urinary organophosphate flame retardant metabolite.
UsesTris(2-chloroethyl) phosphate was used in dynamic air sampling of airborne organophosphate triesters using a solid-phase microextraction device.
DefinitionChEBI: A trialkyl phosphate that is the tris(2-chloroethyl) ester of phosphoric acid.
General DescriptionOdorless clear liquid. Neutral pH.
Reactivity ProfileTris(2-chloroethyl) phosphate is incompatible with strong oxidizing agents and strong bases.
ToxicologyThe toxicological data of tris(2-chloroethyl) phosphate, LD50 values of 390-1410 mg/kg (and more than 2000 mg/kg in one study), have been reported for rats following oral administration. The substance is nonirritating to very mildly irritating to the skin and mucous membranes. It was not sensitizing to the skin in guinea pigs. Subchronic administration of tris(2- chloroethyl) phosphate caused increased liver weight in rats and mice. Additionally, rats showed increased kidney weights and degenerative changes in the hippocampus region of the brain. Results of mutagenicity studies on tris(2- chloroethyl) phosphate are not consistent, but the majority of tests were negative. Results of carcinogenicity studies suggest that tris(2-chloroethyl) phosphate possesses a weak tumorigenic activity, possibly via an epigenetic mechanism. When pregnant rats were treated with tris(2- chloroethyl) phosphate, toxic effects were found in the mother, but no fetotoxic or teratogenic effects were observed. Impairment of reproduction was observed in a two-generation study in mice.
Safety ProfilePoison by intraperitoneal route. Moderately toxic by ingestion. Experimental reproductive effects. Questionable carcinogen with experimental tumorigenic data. A skin and eye irritant. Combustible when exposed to heat or flame. When heated to decomposition it emits very toxic fumes of POx and Cl-. See also PHOSPHATES, CHLORIDES, and ESTERS.
Tris(2-chloroethyl) phosphate Preparation Products And Raw materials
Raw materialsPhosphorus oxychloride-->ETHYLENE OXIDE-->2-Chloroethanol-->Titanium tetrachloride-->Triphenyl phosphite-->Sodium metavanadate-->TRIS(2-CHLOROETHYL) PHOSPHITE
Tag:Tris(2-chloroethyl) phosphate(115-96-8) Related Product Information
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