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N-Acetyl-L-cysteine

N-Acetyl-L-cysteine Suppliers list
Company Name: Capot Chemical Co.,Ltd.
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Products Intro: Product Name:N-Acetyl-L-cysteine
CAS:616-91-1
Purity:98%(Min,HPLC) Package:100g;1kg;5kg,10kg,25kg,50kg
Company Name: Shenzhen Sendi Biotechnology Co.Ltd.
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Products Intro: Product Name:N-Acetyl-cysteine
CAS:616-91-1
Purity:99% Package:127/KG
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Products Intro:Product Name:N-Acetyl-cysteine
CAS:616-91-1
Purity:99% Package:50graM;500graM,1KG; 5KG; 25KG
Company Name: Shenzhen SUNGENING Biological Technology Co., Ltd  Gold
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Products Intro:Product Name:N-Acetyl-L-cysteine
CAS:616-91-1
Purity:99% HPLC Package:10MG;25MG;50MG;100MG
Company Name: Wuhan HongxinKang Fine Chemical Co., Ltd.  Gold
Tel:027-59362599 18674037007
Email:zhuoxingwc@163.com
Products Intro:Product Name:N-Acetyl-cysteine
CAS:616-91-1
Purity:99.99%HPLC Package:1g 100g 1kg 25kg
N-Acetyl-L-cysteine Basic information
Product Name:N-Acetyl-L-cysteine
Synonyms:(S)-ALPHA-AMINO-2-NAPHTHALENEPROPIONIC ACID;RARECHEM BK PT 0097;N-ACETYL CYSTEINE;N-ACETYL-3-MERCAPTOALANINE;N-ACETYL-L-(+)-CYSTEINE;N-ACETYL-L-CYSTEINE;N-ALPHA-ACETYL-L-CYSTEINE;3-(2-NAPHTHYL)-ALANINE
CAS:616-91-1
MF:C5H9NO3S
MW:163.19
EINECS:210-498-3
Product Categories:Phenylalanine analogs and other aromatic alpha amino acids;Amino ACIDS SERIES;Amino Acids;Cysteine [Cys, C];Ac-Amino Acids;Amino Acids (N-Protected);Antioxidant;Biochemistry;Nutritional Supplements;Pharmaceutical Intermediates;N-Acetyl-Amino acid series;Miscellaneous Compounds;Amino Acids & Derivatives;MUCOMYST;amino;Amino acid
Mol File:616-91-1.mol
N-Acetyl-L-cysteine Structure
N-Acetyl-L-cysteine Chemical Properties
Melting point 106-108 °C(lit.)
alpha -35.1 ºC (c=2,H2O)
refractive index 24 ° (C=JPC Method)
storage temp. 2-8°C
solubility H2O: 100 mg/mL with heating
form Solid
color White
Water Solubility Soluble in water, ethanol, methanol, dimethyl sulfoxide, hot isopropyl alcohol, methyl acetate and ethyl acetate. Insoluble in chloroform and ether.
Merck 14,88
BRN 1724426
Stability:Stable. Incompatible with strong oxidizing agents.
CAS DataBase Reference616-91-1(CAS DataBase Reference)
NIST Chemistry ReferenceAcetylcysteine(616-91-1)
EPA Substance Registry SystemL-Cysteine, N-acetyl-(616-91-1)
Safety Information
Risk Statements 36/37/38
Safety Statements 22-24/25
WGK Germany 3
RTECS HA1660000
10-23
TSCA Yes
HS Code 29309016
Hazardous Substances Data616-91-1(Hazardous Substances Data)
MSDS Information
ProviderLanguage
N-Acetyl-L-(+)-cysteine English
SigmaAldrich English
ACROS English
ALFA English
N-Acetyl-L-cysteine Usage And Synthesis
DescriptionN-acetylcysteine amide is a kind of membrane penetrating antioxidant. It has anti-inflammatory activity through regulating the activation of NF-κB and HIF-1α as well as modulation of ROS. It can penetrate across the membrane, replenishes intracellular and glutathione and GSH to help the cell fight against oxidative stress. For these reasons, it has the potential for the treatment of neurodegeneration (such as Parkinson’s disease), radiation exposure and other disorders caused by oxidation. Moreover, it can also attenuate the allergic airway diseases.
Chemical PropertiesWhite crystalline powder
UsesA metabolite of Methyl Isocyanate.
UsesAn antioxidant mucolytic acetylated amino acid.
DefinitionChEBI: An N-acetyl-L-amino acid that is the N-acetylated derivative of the natural amino acid L-cysteine.
Referenceshttp://www.sigmaaldrich.com/catalog/product/sigma/a0737?lang=en&region=US
Grinberg, L, et al. "N-acetylcysteine amide, a novel cell-permeating thiol, restores cellular glutathione and protects human red blood cells from oxidative stress." Free Radical Biology & Medicine 38.1(2005):136-145.
Zhang, Xinsheng, et al. "N-Acetylcysteine Amide Protects Against Methamphetamine-Induced Oxidative Stress and Neurotoxicity in Immortalized Human Brain Endothelial Cells." Brain Research1275(2009):87-95.
Penugonda, S, et al. "Effects of N-acetylcysteine amide (NACA), a novel thiol antioxidant against glutamate-induced cytotoxicity in neuronal cell line PC12."Brain Research 1056.2(2005):132.
Lee, Kyung Sun, et al. "A novel thiol compound, N-acetylcysteine amide, attenuates allergic airway disease by regulating activation of NF-|[kappa]|B and hypoxia-inducible factor-1|[alpha]|." Experimental & Molecular Medicine 39.6(2007):756.
N-Acetyl-L-cysteine Preparation Products And Raw materials
Raw materialsChloroform-->Activated carbon,decolor-->L-Cysteine-->Praseodymium(III) nitrate hexahydrate-->HEROIN DIACETYLMORPHINE
Tag:N-Acetyl-L-cysteine(616-91-1) Related Product Information
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