蛙皮素
中文名称 | 蛙皮素 |
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中文同义词 | 黄蛙素;两栖蓝素;蛙皮素,胃泌素;铃蟾肽;蛙皮素;蛙皮素, ≥97% (HPLC);BOMBESIN ACETATE SALT HYDRATE 蛙皮素;BOMBESIN肽 |
英文名称 | Bombesin |
英文同义词 | Bombesin hydrate acetate salt;Bombesin acetate salt hydrate;2-l-glutamine-6-l-asparagine-alytesi;bombesin acetate;Bombesin, Free Base;BOMBESIN SYNTHETIC >97% STIMULATES GASTR IN RE;BOMBESIN;bombesin acetate hydrate |
CAS号 | 31362-50-2 |
分子式 | C71H110N24O18S |
分子量 | 1619.85 |
EINECS号 | |
相关类别 | 多肽类;细胞生物学;蛋白质/多肽;细胞信号和神经生物学;多肽;多肽-客户肽;Peptide;Neuromedins and related;目录肽;目录多肽 |
Mol文件 | 31362-50-2.mol |
结构式 |
蛙皮素 性质
密度 | 1.50±0.1 g/cm3(Predicted) |
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储存条件 | Keep in dark place,Inert atmosphere,Store in freezer, under -20°C |
溶解度 | 0.05M乙酸:20 mg/mL,澄清,无色 |
形态 | 粉末 |
酸度系数(pKa) | 13.04±0.46(Predicted) |
颜色 | 白色至米白色 |
旋光性 (optical activity) | -20.624〔DMF-HMPT(8:2)〕 |
Merck | 13,1320 |
BRN | 9611365 |
序列 | Pyr-Gln-Arg-Leu-Gly-Asn-Gln-Trp-Ala-Val-Gly-His-Leu-Met-NH2 |
Bombesin is a tetradecapeptide with a COOH terminus ending in Gly-His-Leu-Met-NH2 and subsequently is shown to closely resemble two mammalian bombesin -related peptides, gastrin-releasing peptide (GRP) and neuromedin B (NMB). Bombesin is found to have stimulatory effects upon gastric and pancreatic secretions, release of gastrointestinal hormones, gallbladder contraction and bronchoconstriction. It is present in amphibian gastric endocrine cells, avian proventriculus endocrine cells and avian brain. In mammals it is present mainly in nerve cells and fibers. The only mammalian endocrine cell shown to date to have bombesin is the P-cell in fetal lung. Bombesin is also found in mammalian brain, with its highest concentration in the hypothalamus. Bombesin is shown to be a potent mitogen for Swiss 3T3 cells. In the presence of a low concentration (3.5%) of serum, bombesin stimulates 3T3 cell proliferation. In serum-free medium, bombesin induces DNA synthesis in the absence of any other added growth factor (IC 50 =1 nM).
纯度(HPLC) ≥98.0%
醋酸根含量≤12.0%
水分含量≤8.0%
肽含量≥80.0%
内毒素≤50EU/mg
氨基酸组成分析≤±10%
提供商 | 语言 |
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英文
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更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
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2024/08/19 | HY-P0195 | 蛙皮素 Bombesin | 31362-50-2 | 1mg | 900元 |
2024/08/19 | HY-P0195 | 蛙皮素 Bombesin | 31362-50-2 | 5mg | 1800元 |