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| | 4-METHYLUMBELLIFERYL-ALPHA-D-GLUCOPYRANOSIDE HYDRATE Basic information |
| | 4-METHYLUMBELLIFERYL-ALPHA-D-GLUCOPYRANOSIDE HYDRATE Chemical Properties |
| Melting point | 171-173 °C | | Boiling point | 626.9±55.0 °C(Predicted) | | density | 1.522±0.06 g/cm3(Predicted) | | storage temp. | 2-8°C | | solubility | DMSO: 50 mg/mL, clear, colorless to faintly yellow | | form | White solid | | pka | 12.73±0.70(Predicted) | | color | White to Off-White | | BRN | 1690776 | | InChIKey | YUDPTGPSBJVHCN-JZYAIQKZSA-N | | CAS DataBase Reference | 17833-43-1(CAS DataBase Reference) |
| | 4-METHYLUMBELLIFERYL-ALPHA-D-GLUCOPYRANOSIDE HYDRATE Usage And Synthesis |
| Description | 4-Methylumbelliferyl-α-D-glucopyranoside is a fluorogenic substrate for α-glucosidase. 4-Methylumbelliferyl-α-D-glucopyranoside is cleaved by α-glucosidase to release the fluorescent moiety 4-methylumbelliferyl (4-MU). 4-MU fluorescence is pH-dependent with excitation maxima of 320 and 360 nm at low (1.97-6.72) and high pH (7.12-10.3), respectively, and an emission maximum ranging from 445 to 455 nm, increasing as pH decreases. 4-Methylumbelliferyl-α-D-glucopyranoside has been used to quantify α-glucosidase activity in infant blood spot samples as a biomarker of Fabry and Pompe diseases, lysosomal storage disorders characterized by a deficiency in the enzyme. | | Chemical Properties | white to off-white crystalline powder | | Uses | 4-Methylumbelliferyl α-D-glucopyranoside is used as a flurogenic substrate for the identification, characterization and kinetic analysis of α-D-glucosidase(s). | | Uses | 4-Methylumbelliferyl-α-D-glucopyranoside is a fluorogenic substrate in the assay of a-glucosidase,it has been used in the study of Pompe disease. | | Definition | ChEBI: 4-Methylumbelliferyl-alpha-D-glucopyranoside is a member of coumarins and a glycoside. | | Purification Methods | Recrystallise 4-methylumbellifer-7-yl--D-glucopyranoside from hot H2O or EtOH. [Courtin-Duchateau & Veyrière Carbohydr Research 65 23, 29 1978, Beilstein 18 IV 443.] |
| | 4-METHYLUMBELLIFERYL-ALPHA-D-GLUCOPYRANOSIDE HYDRATE Preparation Products And Raw materials |
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