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Methanesulfonamide

Methanesulfonamide Suppliers list
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CAS:3144-09-0
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Methanesulfonamide manufacturers

  • Methanesulfonamide
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  • $10.00/ kg
  • 2024-04-22
  • CAS:3144-09-0
  • Min. Order: 1kg
  • Purity: 99.7%
  • Supply Ability: 200000kg
  • Methansulfonamid
  • Methansulfonamid pictures
  • $6.00 / 1KG
  • 2024-01-18
  • CAS:3144-09-0
  • Min. Order: 1KG
  • Purity: 99%
  • Supply Ability: g-kg-tons, free sample is available
  • Methanesulfonamide
  • Methanesulfonamide pictures
  • $0.00 / 25KG
  • 2023-06-27
  • CAS:3144-09-0
  • Min. Order: 1KG
  • Purity: 99%
  • Supply Ability: 50000KG/month
Methanesulfonamide Basic information
Product Name:Methanesulfonamide
Synonyms:Methylsulfonamid;METHYL SULFONYLAMINE;LABOTEST-BB LT00153664;Methanesulfonamide, 98+%;Methanesulphonamide,98+%;Methanesulfonyl amide;MethanesulfonaMid;Methanesulfomide
CAS:3144-09-0
MF:CH5NO2S
MW:95.12
EINECS:221-553-6
Product Categories:Pharmaceutical Intermediates
Mol File:3144-09-0.mol
Methanesulfonamide Structure
Methanesulfonamide Chemical Properties
Melting point 85-89 °C(lit.)
Boiling point 208.2±23.0 °C(Predicted)
density 1.229 (estimate)
refractive index 1.5130 (estimate)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility Slightly soluble in DMSO and methanol.
form Crystals, Powder or Flakes
pka10.87±0.60(Predicted)
color White to yellow
BRN 1740835
InChIKeyHNQIVZYLYMDVSB-UHFFFAOYSA-N
CAS DataBase Reference3144-09-0(CAS DataBase Reference)
NIST Chemistry ReferenceMethane sulfonamide(3144-09-0)
EPA Substance Registry SystemMethanesulfonamide (3144-09-0)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36-24/25
WGK Germany 3
TSCA T
HazardClass IRRITANT
HS Code 29350090
MSDS Information
ProviderLanguage
Methanesulfonamide English
SigmaAldrich English
ACROS English
ALFA English
Methanesulfonamide Usage And Synthesis
Chemical PropertiesWhite to yellow crystals, powder or flakes
Uses
  • Methanesulfonamide is used in the synthesis of important organic reagents such as N-(2-methylthio-1-p-toluenesufonyl)methanesulfonamide and tert-butyl ((2-(trimethylsilyl)ethyl)sulfonyl)carbamate.
  • It can be used as a source of nitrogen in the conversion of carboxylic acids to corresponding nitriles.
  • It is widely used as a reagent in the synthesis of medicinally important compounds such as derivatives of indole-N-acetamide, methanesulfonamide pyrimidine-substituted 3,5-dihydroxy-6-heptenoates and repertaxin.

UsesMethanesulfonamide will react with thionyl chloride, cyanates, carbon disulfide and ketones and aldehydes to prepare pharmaceuticals, brightening agent and other target molecules. It is also used in biological studies to predict binding affinity and binding mode of protein ligand complexes.
Synthesis Reference(s)Journal of the American Chemical Society, 90, p. 4096, 1968 DOI: 10.1021/ja01017a032
The Journal of Organic Chemistry, 60, p. 7682, 1995 DOI: 10.1021/jo00128a048
Tetrahedron Letters, 35, p. 7201, 1994 DOI: 10.1016/0040-4039(94)85360-6
Tag:Methanesulfonamide(3144-09-0) Related Product Information
3-Aminobenzenesulfonamide Cyclopropanesulfonamide TRIFLUOROMETHANESULFONYL FLUORIDE Trifluoromethanesulfonamide Sulfamide Dimethyl sulfone Sodium carboxymethyl cellulose N,N-Dimethylformamide Sulfanilamide Benzenesulfonamide p-Toluenesulfonamide Ethanesulfonamide DANSYL HYDRAZINE N-Phenyl-bis(trifluoromethanesulfonimide) ACID VIOLET 5 TPCK 4-AMINOSULFONYL-1-HYDROXY-2-NAPHTHOIC ACID, 97 p-Toluenesulfonyl Isocyanate