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BOC Sciences
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Product Name:1-Palmitoyl lysophosphatidic acid
CAS:22002-85-3
Purity:98% Package:1G;10G;100G Remarks:1-Palmitoyl lysophosphatidic acid (1-Palmitoyl LPA) is a LPA analog containing palmitic acid at the sn-1 position. LPA binds to one of at least five different G protein-coupled receptors to mediate a
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Shanghai Hongye Biotechnology Co. Ltd
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Product Name:1-Palmitoyl Lysophosphatidic Acid
CAS:22002-85-3
Purity:>98% Package:1mg;10mg;50mg;100mg;
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ChemeGen(Shanghai) Biotechnology Co.,Ltd.
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Product Name:1-Palmitoyl Lysophosphatidic Acid
CAS:22002-85-3
Purity:98% Package:10 mg;50 mg;100 mg;500 mg;1 g;5 g;10 g
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MedBioPharmaceutical Technology Inc
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Product Name:2-hydroxy-3-(phosphonooxy)propyl palmitate
CAS:22002-85-3
Purity:98% Package:10mg; 1mg; 5mg; 25mg Remarks:Medbio
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Shaanxi Dideu Newmaterial Co., Ltd.
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Product Name:2-hydroxy-3-(phosphonooxy)propyl palmitate
CAS:22002-85-3
Purity:98%
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| | 2-hydroxy-3-(phosphonooxy)propyl palmitate Basic information |
| Product Name: | 2-hydroxy-3-(phosphonooxy)propyl palmitate | | Synonyms: | 2-hydroxy-3-(phosphonooxy)propyl palmitate;1-Palmitoyl lysophosphatidic acid;2-hydroxy-3-(phosphonooxy)propyl ester Hexadecanoic acid;Palmitic acid 2-hydroxy-3-(phosphonooxy)propyl ester;Einecs 244-707-4;Hexadecanoic acid, 2-hydroxy-3-(phosphonooxy)propyl ester;1-Palmitoyl Lysophosphatidic Acid Exclusive;1-Palmitoyl Lysophosphatidic Acid (1-Palmitoyl LPA free acid) | | CAS: | 22002-85-3 | | MF: | C19H39O7P | | MW: | 410.48 | | EINECS: | 2447074 | | Product Categories: | | | Mol File: | 22002-85-3.mol |  |
| | 2-hydroxy-3-(phosphonooxy)propyl palmitate Chemical Properties |
| Boiling point | 560.6±60.0 °C(Predicted) | | density | 1.112±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMF: 2 mg/ml; DMSO: 2.5 mg/ml; Ethanol: 25 mg/ml; PBS (pH 7.2): 3 mg/ml | | form | A crystalline solid | | pka | 1.82±0.10(Predicted) |
| | 2-hydroxy-3-(phosphonooxy)propyl palmitate Usage And Synthesis |
| Description | 1-Palmitoyl lysophosphatidic acid (1-Palmitoyl LPA) is a LPA analog containing palmitic acid at the sn-1 position. LPA binds to one of at least five different G protein-coupled receptors to mediate a variety of biological responses including cell proliferation, smooth muscle contraction, platelet aggregation, neurite retraction, and cell motility.1,2 Additionally, 1-palmitoyl LPA enhances the action of β-lactam antibiotics (ampicillin, piperacillin, and ceftazidime) on various strains of P. aeruginosa, a pathogen associated with pulmonary disease and pneumonia, via binding both Ca2+ and Mg2+.3 | | Definition | ChEBI: 1-palmitoylglycerol 3-phosphate is a monoacylglycerol phosphate having palmitoyl as the acyl group on O-1 and with the phosphate group on O-3. It is a conjugate acid of a 1-palmitoylglycerol 3-phosphate(2-). | | References | 1. Noguchi, K., Ishii, S., and Shimizu, T. Identification of p2y9/GPR23 as a novel G protein-coupled receptor for lysophosphatidic acid, structurally distant from the Edg family J. Biol. Chem. 278(28),25600-25606(2003).
2. Moolenaar, W.H. LPA: A novel lipid mediator with diverse biological actions Trends Cell Biol. 4(6),213-219(1994).
3. Krogfelt, K.A., Utley, M., Krivan, H.C., et al. Specific phospholipids enhance the activity of β-lactam antibiotics against Pseudomonas aeruginosa J. Antimicrob. Chemother. 46(3),377-384(2000). |
| | 2-hydroxy-3-(phosphonooxy)propyl palmitate Preparation Products And Raw materials |
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