- Beta-Mangostin
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- $180.00 / 1kg
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2024-04-23
- CAS:20931-37-7
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: 20ton
- Beta-mangostin
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- $0.00 / 10MG
-
2024-04-23
- CAS:20931-37-7
- Min. Order: 10MG
- Purity: ≥98% HPLC
- Supply Ability: 100KG
- β-mangostin
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- $0.00 / 5mg
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2023-02-24
- CAS:20931-37-7
- Min. Order: 5mg
- Purity: ≥95%(HPLC)
- Supply Ability: 10 g
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| | Beta-mangostin Basic information |
| Product Name: | Beta-mangostin | | Synonyms: | Beta-mangostin;1,6-Dihydroxy-3,7-dimethoxy-2,8-bis(3-methyl-2-butenyl)-9H-xanthen-9-one;1,6-Dihydroxy-3,7-dimethoxy-2,8-bis(3-methyl-2-buten-1-yl)-9H-xanthen-9-one;Beta-mangostin
β-Mangostin;β-Mangostin, 98%, from Garcinia mangostana L.;beta-Mangostin, >98%;Keywords Dianthus extract;shanzhuguoduofen | | CAS: | 20931-37-7 | | MF: | C25H28O6 | | MW: | 424.49 | | EINECS: | | | Product Categories: | reagent;standard substance | | Mol File: | 20931-37-7.mol |  |
| | Beta-mangostin Chemical Properties |
| Melting point | 175-176℃ | | Boiling point | 616.5±55.0 °C(Predicted) | | density | 1.212 | | storage temp. | 2-8°C | | solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | | form | powder | | pka | 7.05±0.20(Predicted) | | color | Yellow | | Stability: | Light Sensitive |
| | Beta-mangostin Usage And Synthesis |
| Description | β-Mangostin is a xanthone originally isolated from G. mangostana with diverse biological activites. It inhibits growth of methicillin-resistant S. aureus (MRSA) and methicillin-susceptible S. aureus (MSSA; MICs = 6.25-12.5 and 6.25-25 μg/ml, respectively), P. falciparum (IC50 = 3 μg/ml), and M. tuberculosis (MIC = 6.25 μg/ml). β-Mangostin inhibits fatty acid synthase (FASN) with an IC50 value of 24.83 μM. It induces cell cycle arrest at the G2/M phase and intrinsic and mitochondrial apoptosis in MCF-7 breast cancer cells. β-Mangostin also inhibits LPS-induced nitric oxide and prostaglandin E2 (PGE2; ) production in RAW264.7 cells and reduces neutrophil infiltration and TNF-α and IL-1β production in a mouse model of carrageenan-induced peritonitis. | | Uses | β-Mangostin is isolated from the stem bark of Garcinia mangostana L. which shows significant cytotoxicities and anti-inflammatory activities against the LPS-induced RAW cell 264.7. Also, it demonstrates anti-metastatic activity against human hepatocellular carcinoma (HCC) cells, which may act as a promising therapeutic agent for the treatment of HCC. | | Definition | ChEBI: Beta-Mangostin is a member of xanthones. |
| | Beta-mangostin Preparation Products And Raw materials |
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