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BOC Sciences
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Product Name:ML 236A
CAS:58889-19-3
Remarks:It has the activity of inhibiting HMG-CoA reductase, and it is produced by the strain of Penicillum
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| | ML 236A Basic information |
| Product Name: | ML 236A | | Synonyms: | ML 236A;(4R)-4α-Hydroxy-6β-[2-[(1S)-2β-methyl-8α-hydroxy-1,2,6,7,8,8aβ-hexahydronaphthalene-1β-yl]ethyl]tetrahydro-2H-pyran-2-one;(4R)-6β-[2-[(1S)-1,2,6,7,8,8aβ-Hexahydro-8α-hydroxy-2β-methylnaphthalene-1β-yl]ethyl]tetrahydro-4α-hydroxy-2H-pyran-2-one;6β-[2-[[(1S)-1,2,6,7,8,8aβ-Hexahydro-8α-hydroxy-2β-methylnaphthalen]-1β-yl]ethyl]tetrahydro-4α-hydroxy-2H-pyran-2-one;DesmethylmonacolinJ;Compactin diol lactone;2H-Pyran-2-one, 6-[2-[(1S,2S,8S,8aR)-1,2,6,7,8,8a-hexahydro-8-hydroxy-2-methyl-1-naphthalenyl]ethyl]tetrahydro-4-hydroxy-, (4R,6R)- | | CAS: | 58889-19-3 | | MF: | C18H26O4 | | MW: | 306.399 | | EINECS: | | | Product Categories: | | | Mol File: | 58889-19-3.mol |  |
| | ML 236A Chemical Properties |
| Melting point | 126-132 °C | | Boiling point | 535.2±50.0 °C(Predicted) | | density | 1.19±0.1 g/cm3(Predicted) | | pka | 13.49±0.40(Predicted) |
| | ML 236A Usage And Synthesis |
| Definition | ChEBI: Compactin diol lactone is a carbobicyclic compound that is ML-236C substituted by a hydroxy group at position 8S. It is a fungal metabolite isolated from Penicillium citrinum and exhibits anticholesteremic activity. It has a role as a fungal metabolite, an EC 1.1.1.34/EC 1.1.1.88 (hydroxymethylglutaryl-CoA reductase) inhibitor, an antilipemic drug, an antiatherosclerotic agent, an anticholesteremic drug and an antimicrobial agent. It is a carbobicyclic compound, a member of 2-pyranones, a member of hexahydronaphthalenes, a secondary alcohol and a polyketide. It is functionally related to a ML-236C. |
| | ML 236A Preparation Products And Raw materials |
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