ChemicalBook > Product Catalog >Chemical Reagents >Organic reagents >fatty acid >beta-Hydroxyisovaleric Acid

beta-Hydroxyisovaleric Acid

beta-Hydroxyisovaleric Acid Suppliers list
Company Name: Hebei Mojin Biotechnology Co., Ltd
Tel: +86-13288715578 +86-13231137666
Email: sales@hbmojin.com
Products Intro: Product Name:beta-Hydroxyisovaleric Acid
CAS:625-08-1
Purity:99% Package:25KG
Company Name: Capot Chemical Co.,Ltd.
Tel: 571-85586718 +8613336195806
Email: sales@capotchem.com
Products Intro: Product Name:3-Hydroxy-3-Methyl butanoic Acid
CAS:625-08-1
Purity:95%(Min,GC) Package:1G;1KG;100KG
Company Name: Shanghai Daken Advanced Materials Co.,Ltd
Tel: +86-371-66670886
Email: info@dakenam.com
Products Intro: Product Name:BETA-HYDROXYISOVALERIC ACID
CAS:625-08-1
Purity:99% Package:100g ;1KG ;5KG 25KG
Company Name: Henan Tianfu Chemical Co.,Ltd.
Tel: +86-0371-55170693 +86-19937530512
Email: info@tianfuchem.com
Products Intro: Product Name:beta-Hydroxyisovaleric Acid
CAS:625-08-1
Purity:99% Package:25KG;5KG;1KG
Company Name: ATK CHEMICAL COMPANY LIMITED
Tel: +undefined-21-51877795
Email: ivan@atkchemical.com
Products Intro: Product Name:Beta-Hydroxyisovaleric acid
CAS:625-08-1
Purity:98% Package:25G;50G;100G;500G;1KG;10KG;50KG

beta-Hydroxyisovaleric Acid manufacturers

Related articles

beta-Hydroxyisovaleric Acid Basic information
Product Name:beta-Hydroxyisovaleric Acid
Synonyms:RARECHEM AL BO 2324;?Hydroxyisovaleric acid;β-Hydroxy-β-MethylButyric acid;(S)-2-Hydroxyisovaleric Acid;3-B-HYDROXYBUTYRIC ACID;BETA-HYDROXYISOVALERIC ACID;BETA-HYDROXY-3-METHYL BUTYRIC ACID;HYDROXYISOVALERIC ACID, BETA-
CAS:625-08-1
MF:C5H10O3
MW:118.13
EINECS:626-699-8
Product Categories:Diagnostic;Intermediates & Fine Chemicals;Metabolites & Impurities;Pharmaceuticals;Diagnostic, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals;Pharmaceutical Raw Materials
Mol File:625-08-1.mol
beta-Hydroxyisovaleric Acid Structure
beta-Hydroxyisovaleric Acid Chemical Properties
Melting point ?80 °C (lit.)
Boiling point 88 °C/1 mmHg (lit.)
density 0.938 g/mL at 25 °C (lit.)
refractive index n20/D 1.4415(lit.)
Fp 113 °C
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility DMF:10.0(Max Conc. mg/mL);84.65(Max Conc. mM)
DMSO:10.0(Max Conc. mg/mL);84.65(Max Conc. mM)
Ethanol:10.0(Max Conc. mg/mL);84.65(Max Conc. mM)
PBS (pH 7.2):10.0(Max Conc. mg/mL);84.65(Max Conc. mM)
pka4.38±0.10(Predicted)
form Liquid
Specific Gravity1.10
color Pale yellow
Water Solubility Soluble in water and ethanol.
BRN 1743952
InChIKeyAXFYFNCPONWUHW-UHFFFAOYSA-N
CAS DataBase Reference625-08-1(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36
RIDADR UN 3334
WGK Germany 3
10-13-21
HS Code 29181990
MSDS Information
ProviderLanguage
SigmaAldrich English
ALFA English
beta-Hydroxyisovaleric Acid Usage And Synthesis
Descriptionβ-Hydroxy β-methylbutyric acid (HMB), or β-hydroxy β- methylbutyrate, is a metabolite of the essential amino acid leucine and is synthesized in the human body. It plays a part in protein synthesis and was discovered by Dr. Steven L. Nissen at Iowa State University. It has been used in scientific studies to purportedly increase muscle mass and decrease muscle breakdown. Nissen held the original patent on the metabolite as a nutritional supplement. It was discovered in pigs, and small quantities can also be found in grapefruit, alfalfa, and catfish. As a supplement it is usually sold as a calcium salt.
Research published in the Journal of Applied Physiology has shown that HMB may have an effect on increasing muscle weight and strength. A review in Nutrition & Metabolism provides an in depth and objective analysis of HMB research. The same study lists as HMB' s proposed mechanisms of action the following:
Increased sarcolemmal integrity via conversion to HMG-CoA
Enhanced protein synthesis via the mTOR pathway
Depression of protein degradation through inhibition of the ubiquitin pathway
Three grams of Calcium beta-hydroxy-beta-methylbutyrate per day may help muscles combat protein breakdown, assist in muscle repair and support increased endurance. Studies suggest its benefits may be greater for the untrained. Also, well-controlled scientific studies have found increases in muscle mass and decreases in body fat in 70 year old men. It has helped patients with chronic obstructive pulmonary disease in hospital intensive care units, muscle wasting associated with HIV or AIDS and with cancer, and trauma victims with severe injuries.
The human body produces about 0.2 - 0.4 grams per day. Standard doses in research studies have been 1.5 to 3.0 grams per day, usually divided into two doses.
Chemical Propertiescolorless to light yellow liquid
Uses3-Hydroxy-3-methylbutyric acid is a useful biochemical for synthesis and proteomics research. It is used as an indicator of biotin deficiency. Further, it is used to increase muscle mass and decrease muscle breakdown. In addition to this, it is involved in the protein synthesis.
Usesβ-Hydroxyisovaleric Acid is a metabolite of the essential amino acid Leucine and is synthesized in the human body. Studies suggest that β-Hydroxyisovaleric Acid may have an effect on increasing muscle weight and strength. The presence of elevated β-Hydroxyisovaleric Acid is a sensitive marker of biotin deficiency and may indicate the presence of a genetic disorder such as biotinidase deficiency or holocarboxylase synthetase deficiency.
DefinitionChEBI: A 3-hydroxy monocarboxylic acid that is isovaleric acid substituted at position 3 by a hydroxy group. Used as indicator of biotin deficiency.
beta-Hydroxyisovaleric Acid Preparation Products And Raw materials
Preparation Products3-Methyl-1,3-butanediol
Tag:beta-Hydroxyisovaleric Acid(625-08-1) Related Product Information
β-Hydroxyisovaleric Acid-d8 Sodium citrate 3-HYDROXY-3-METHYLGLUTARIC ACID Alverine citrate Ammonium citrate dibasic TEREBIC ACID Triethyl citrate SODIUM DIHYDROGEN CITRATE FERRIC CITRATE TRIMETHYL CITRATE oxeladin Ethyl 3-methyl-3-phenylglycidate Tributyl citrate AGARIC ACID Citric acid Ammonium ferric citrate BETA-HYDROXYISOVALERIC ACID CALCIUM SALT HYDRATE LITHIUM CITRATE, 99