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Dutasteride Suppliers list
Company Name: Shenzhen Sendi Biotechnology Co.Ltd.
Tel: 0755-23311925 18102838259
Products Intro: Product Name:Dutasteride
Purity:99% Package:71/G
Company Name: Henan Tianfu Chemical Co.,Ltd.
Tel: 0371-55170693
Products Intro: CAS:164656-23-9
Purity:99% Package:500G;1KG;5KG;25KG
Company Name: Mainchem Co., Ltd.
Tel: +86-0592-6210733
Products Intro: Product Name:Dutasteride
Company Name: PI & PI BIOTECH INC.
Tel: 020-81716320
Products Intro: Product Name:Dutasteride
Purity:90%+ Package:10mg, 25mg, 50mg, 100mg, Other scale please email
Company Name: Hubei XinRunde Chemical Co., Ltd.
Tel: +8615102730682; +8618874586545
Products Intro: Product Name:Dutasteride
Purity:99% Package:1KG;10USD Remarks:White Crystalline Solid

Lastest Price from Dutasteride manufacturers

  • Dutasteride
  • US $10.00 / KG
  • 2018-04-13
  • CAS:164656-23-9
  • Min. Order: 10G
  • Purity: 99%
  • Supply Ability: 10MT
Dutasteride Basic information
Indications and Usage Mechanisms of Action Clinical Research Side Effects Contradictions
Product Name:Dutasteride
Synonyms:(1S,2R,7R,10S,11S,14S,15S)-N-[2,5-bis(trifluoroMethyl)phenyl]-2,15-diMethyl-5-oxo-6-azatetracyclo[^{2,7}.0^{11,15}]heptadec-3-ene-14-carboxaMide;(4aR,4bS,6aS,7S,9aS,9bS,11aR)-N-[2,5-Bis(trifluoroMethyl)phenyl]-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-4a,6a-diMethyl-2-oxo-1H-Indeno[5,4-f]quinoline-7-carboxaMide;(5α,17β)-;(4aR,4bS,6aS,7S,9aS,9bS,11aR)-N-[2,5-Bis(trifluoroMethyl)phenyl]-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-4a,6a-diMethyl-2-oxo-1H-indeno[5,4-f]quinoline-7-carboxaMide-13C6;6β-Hydroxy Dutasteride;4-Azaandrost-1-ene-17-carboxaMide, N-[2,5-bis(trifluoroMethyl)phenyl]-3-oxo-, (5a,17b)-;Avolve;Dutasteride API
Product Categories:Hormone Drugs;API;Miscellaneous Biochemicals;All Inhibitors;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;Steroids;Steroid and Hormone
Mol File:164656-23-9.mol
Dutasteride Structure
Dutasteride Chemical Properties
Melting point 242-250°C
storage temp. -20°C Freezer
solubility DMSO: soluble2mg/mL, clear
color white to beige
Safety Information
MSDS Information
Dutasteride Usage And Synthesis
Indications and UsageDutasteride is the first and only double 5α reductase inhibitor used to treat prostatic hyperplasia, and it is mainly used clinically to treat prostate enlargement, male-pattern hair loss, seborrheic hair loss, and hereditary hair loss.
Mechanisms of ActionThe human body contains type I and type II 5α reductase, with type II found mainly in the prostate, and type I found mainly in the liver and skin. 5α reductase is the main cause for continuous benign prostate enlargement; it promotes the transformation of testosterone in patients’ prostate into the more active dihydrotestosterone, thus causing prostate cells to enlarge and the prostate to swell. Dutasteride can inhibit both type I and II 5α reductase at the same time. This type of simultaneous inhibiting mechanism can rapidly and continuously reduce prostate size, dramatically improve urination, and reduce the risk fo acute urinary retention and its related prostate surgeries.
Clinical ResearchThe American FDA approved a 2-year multicenter randomized double-blind control clinical trial – the first long term clinical assessment of the combined usage of Dutasteride and α receptor blockers. Included subjects were male patients with moderate to severe prostate enlargement (ages greater than or equal to 50, prostate volume (PV) ≥30 cc, serum prostate specific antigen (PSA) levels 1.5-10ng/ml, 5ml/sec < maximum urinary flow (Qmax) ≤15ml/sec, minimum urination ≥ 125ml, international prostate symptom score (IPSS) ≥ 12). Patients were first given a placebo for 4 weeks and then were randomly given either 0.5mg/day of Dutasteride and 0.4mg/day of Tamsulosin, only 0.5mg/day of Dutasteride, or only 0.4mg/day of Tamsulosin.
Results showed: After 12-24 months, the combined usage of Dutasteride with Tamsulosin had better curative effects than did individual usage.
Side EffectsErectile dysfunction, reduced libido, breast diseases (including enlarged or swelling breasts), ejaculation difficulties and dizziness.
ContradictionsNot to be used by women and children.
Chemical PropertiesWhite Crystalline Solid
UsesUsed in the treatment of benign prostatic hyperplasia. Dual inhibitor of 5a-reductase isoenzymes type 1 and 2; structurally related to Finasteride.
UsesUsed in the treatment of benign prostatic hyperplasia. Dual inhibitor of 5α-reductase isoenzymes type 1 and 2; structurally related to Finasteride.
Usesantihypertensive, ACE inhiibitor
UsesDutasteride is a dual inhibitor of 5α-reductase isoenzymes type 1 and 2; structurally related to Finasteride (F342000). Dutasteride is used in the treatment of benign prostatic hyperplasia.
DefinitionChEBI: Finasteride in which the tert-butyl group is replaced by a 2,5-bis(trifluoromethyl)phenyl group. A synthetic 4-azasteroid, dutasteride is a selective inhibitor of both the type 1 and type 2 isoforms of steroid 5alpha-reductase an intracellular enzyme that converts testosterone to 5alpha-dihydrotestosterone. Dutasteride is used for the treatment of symptomatic benign prostatic hyperplasia in men with an enlarged prostate gland.
Dutasteride Preparation Products And Raw materials
Tag:Dutasteride(164656-23-9) Related Product Information
Dutasteride-13C6 5-METHYL-2-(TRIFLUOROMETHYL)ANILINE 3'-TRIFLUOROMETHYL-2-METHYLVALERANILIDE 3'-TRIFLUOROMETHYLCYCLOPENTANECARBOXANILIDE 1,4-BIS(DIFLUOROMETHYL)BENZENE N-(1-METHYLUNDECYL) ACRYLAMIDE N-cyclodecylmethylamine alpha,alpha,alpha,alpha',alpha'-pentafluoro-o-xylene N-DODECYLACRYLAMIDE 2,5-Bis(trifluoromethyl)aniline 1,4-Bis(trifluoromethyl)-benzene N-(2,5-dimethylphenyl)butanamide Dutasteride Finasteride PHENYL VALERATE PHENYL RESIN Phenylacetic acid Diphenyl ether