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Finasteride

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Company Name: Shenzhen Sendi Biotechnology Co.Ltd.
Tel: 0755-23311925 18102838259
Email: Abel@chembj.com
Products Intro: Product Name:Finasteride
CAS:98319-26-7
Purity:99% Package:9900/KG
Company Name: VOT INTERNATIONAL BUSINESS CO.,LTD  Gold
Tel:0536-2456718
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Products Intro:Product Name:finasteride
CAS:98319-26-7
Package:25kgs
Company Name: Shanghai Norky Pharmaceutical Co., Ltd.   Gold
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Products Intro:CAS:98319-26-7
Company Name: Guangzhou Kafen Biotech Co.,Ltd  Gold
Tel:020-31121484 18027468163 QQ:2355327168
Email:gy@yccreate.com
Products Intro:Product Name:Finasteride
CAS:98319-26-7
Purity:99% Package:1KG;5KG;25KG
Company Name: J & K SCIENTIFIC LTD.  
Tel:400-666-7788 +86-10-82848833
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Products Intro:Product Name:Finasteride
CAS:98319-26-7
Purity:98.0%(GC) Package:1G,200MG
Finasteride Basic information
Indications and Usage Mechanisms of Action
Product Name:Finasteride
Synonyms:(5alpha,17beta)-(1,1-dimethylethyl)-3-oxo-4-azaandrost-1-ene-17-carboxamide;17beta-(n-tert-butylcarbamoyl)-4-aza-5alpha-androst-1-en-3-one;4-azaandrost-1-ene-17-carboxamide,n-(1,1-dimethylethyl)-3-oxo-,(5-alpha,17-be;4-azaandrost-1-ene-17-carboxamide,n-(1,1-dimethylethyl)-3-oxo-,(5alpha,17beta;l-652,931;mk-0906;n-tert-butyl-3-oxo-4-aza-5alpha-androst-1-ene-17beta-carboxamide;1,(5-ALPHA)-ANDROSTAN-4-AZA-3-ONE-17-BETA-(N-TERT-BUTYL-CARBOXAMIDE)
CAS:98319-26-7
MF:C23H36N2O2
MW:372.54
EINECS:
Product Categories:Active Pharmaceutical Ingredients;API;Biochemistry;Steroids;Steroids (Others);Intermediates & Fine Chemicals;Pharmaceuticals;Vitamin Ingredients;Intracellular receptor;Steroid and Hormone;PROSCAR;Hormone Drugs
Mol File:98319-26-7.mol
Finasteride Structure
Finasteride Chemical Properties
Melting point 253 °C
storage temp. Store at RT
solubility DMSO: 32 mg/mL, soluble
form solid
color white to beige
Water Solubility insoluble
Merck 4082
CAS DataBase Reference98319-26-7(CAS DataBase Reference)
Safety Information
Hazard Codes Xn,T,Xi
Risk Statements 22-61-60-36/37/38
Safety Statements 36/37/39-45-53-36-26-24/25
WGK Germany 3
RTECS CL5245000
Hazardous Substances Data98319-26-7(Hazardous Substances Data)
MSDS Information
ProviderLanguage
SigmaAldrich English
Finasteride Usage And Synthesis
Indications and UsageFinasteride is a basic drug to treat benign prostatic hyperplasia and prostatitis, a synthetic 4-nitrogen steroid hormone compound and a sex hormone drug.
It is used for benign prostatic hyperplasia, men's prostatic fat and other diseases. Finasteride is the only oral drug approved by the US Food and Drug Administration (FDA) to treat male pattern baldness.
Mechanisms of ActionFinasteride can selectively inhibit 5α-reductase, changing the conversion process of testosterone into 5α dihydrotestosterone (DHT), decreasing androgen levels in prostate cells, and prostate-specific antigens in serum, decreasing prostate swelling, and increasing urine flow rate, thereby alleviating the symptoms of prostatic hyperplasia. It acts by selectively blocking androgen stimulation of the prostate, but affects sexual function very rarely. Meanwhile, due to blocking of testosterone conversion and reduced synthesis of dihydrotestosterone, it can reduce dihydrotestosterone levels in the serum and scalp hair follicles, recovering the function of previously inhibited hair follicles, promoting hair growth and preventing loss.
Chemical PropertiesOff-White Crystalline Powder
UsesInhibitor of 5α-reductase, the enzyme which converts testosterone to the more potent androgen, 5α-dihydrotestosterone. Antialopecia agent.
Usesanti-androgen, alpha-reductase inhibitor
UsesTreatment of benign prostatic hyperplasia and androgenetic alopecia
UsesInhibitor of 5a-reductase, the enzyme which converts testosterone to the more potent androgen, 5a-dihydrotestosterone. Antialopecia agent
DefinitionChEBI: An aza-steroid that is a synthetic drug for the treatment of benign prostatic hyperplasia.
Biological ActivityAntiandrogen that inhibits type II 5 α reductase (IC 50 = 65 nM). Suppresses the conversion of testosterone to dihydrotestosterone. Reduces prostatic dihydrotestosterone levels and prostate size in vivo . Orally active.
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