- ACES
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- $1.00 / 1Kg
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2024-02-20
- CAS:7365-82-4
- Min. Order: 1Kg
- Purity: 0.995
- Supply Ability: 1000tons
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| Product Name: | ACES | | Synonyms: | N-(2-ACETAMIDO)-2-AMINOETHANESULPHONIC ACID;N-(CARBAMOYLMETHYL)TAURINE;N-(CARBAMOYLMETHYL)-2-AMINOETHANESULFONIC ACID;TIMTEC-BB SBB006711;ACES,BIOLOGICALBUFFER;N-(2-Acetamido)-2-aminoethanesulphonic acid >99%;N-(2-Acetamido)-2-aminoethanesulfonic Acid [Good's buffer component for biological research];ACES, 99%, EXTRA PURE | | CAS: | 7365-82-4 | | MF: | C4H10N2O4S | | MW: | 182.2 | | EINECS: | 230-908-4 | | Product Categories: | Biochemistry;Good's Buffers;Buffer | | Mol File: | 7365-82-4.mol |  |
| Melting point | >220 °C (dec.)(lit.) | | Boiling point | 404.49℃ | | density | 1.484±0.06 g/cm3(Predicted) | | vapor pressure | 0Pa at 25℃ | | storage temp. | room temp | | solubility | H2O: 0.1 M at 20 °C, clear, colorless | | form | Crystals | | color | White | | PH | 2.5-4.5 (25℃, 0.1M in H2O) | | pka | 6.8(at 25℃) | | PH Range | 6.1 - 7.5 | | Water Solubility | soluble | | λmax | λ: 260 nm Amax: 0.008
λ: 280 nm Amax: 0.005 | | Merck | 14,36 | | BRN | 2253770 | | InChIKey | DBXNUXBLKRLWFA-UHFFFAOYSA-N | | LogP | -4.49 at 25℃ | | CAS DataBase Reference | 7365-82-4(CAS DataBase Reference) | | EPA Substance Registry System | Ethanesulfonic acid, 2-[(2-amino-2-oxoethyl)amino]- (7365-82-4) |
| Description | ACES is a zwitterionic buffering agent used in biochemistry and molecular biology that was first selected and described by Good et al. It is a paraacetamide buffer suitable for environments with a pH of 6.1 - 7.5. ACES can be used as a buffer component in cell culture media for use in agarose and polyacrylamide electrophoresis and in isoelectric focusing of proteins. It forms complexes with most common metals, and the formation constant should be taken into account when using such buffers in solutions containing metal ions. | | Chemical Properties | ACES (N-(Carbamoylmethyl)taurine) is white crystals | | Uses | ACES is used as a Good's buffer is an ideal separator in the resolution of protein systems, a zwitterionic compound used in biochemical and biological research. | | Uses | N-(Carbamoylmethyl)taurine can be used to study biological buffers and zwitterionic compounds. ACES has been used in a study to determine the levels of ibuprofen and flurbiprofen in pharmaceuticals by capillary zone electrophoresis. | | Uses | Buffer for biological systems. | | Definition | ChEBI: ACES (N-(2-acetamido)-2-aminoethanesulfonic acid) is a Good's buffer substance, pKa = 6.9 at 20 ℃. It is an ACES and an amino sulfonic acid. It is a tautomer of a 2-[(2-amino-2-oxoethyl)ammonio]ethanesulfonate. | | Preparation | In the presence of the reaction solvent tetrahydrofuran, add nitrogen-containing reagent ammonia into the reactor to react with the raw material, wherein the molar ratio of ammonia to theraw material is 1:1. The reaction temperature is 60°C, the reaction pressure is 1 MPa (gauge pressure), and the reaction time is 8 hours. After the reaction is completed, it is acidified to generate ACES. Then spin off the solvent tetrahydrofuran, add ethyl acetate, wash twice with water, dry with anhydrous sodium sulfate, and spin off the ethyl acetate to obtain the crude ACES. Purification stepIn the reactor, the purified solvent tetrahydrofuran was added to dissolve the crude ACES, recrystallized at low temperature, the insoluble matter was removed by suction, and the filtrate was rotary evaporated to remove tetrahydrofuran to obtain refined ACES.
 | | Purification Methods | Recrystallise ACES from hot aqueous EtOH. [Perrin & Dempsey Buffers for pH and Metal Ion Control Chapman & Hall, London 1974, Beilstein 4 III 1707.] |
| | ACES Preparation Products And Raw materials |
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