| Company Name: |
J & K SCIENTIFIC LTD.
|
| Tel: |
010-82848833 400-666-7788 |
| Email: |
jkinfo@jkchemical.com |
| Products Intro: |
Product Name:Hexobarbital
CAS:56-29-1
Package:250Mg,25Mg
|
| Company Name: |
Sinopharm Chemical Reagent Co,Ltd.
|
| Tel: |
86-21-63210123 |
| Email: |
sj_scrc@sinopharm.com |
| Products Intro: |
Product Name:Hexobarbital CIII (500 mg)
CAS:56-29-1
Package:500 mg
|
|
| | HEXOBARBITAL Basic information |
| Product Name: | HEXOBARBITAL | | Synonyms: | 5-[1-CYCLOHEXENYL]-1,5-DIMETHYLBARBITURIC ACID;LABOTEST-BB LT00244803;EVIPAL;HEXOBARBITAL;1,5-Dimethyl-5-(1-cyclohexenyl)barbituric acid;1,5-dimethyl-5-(1-cyclohexenyl)barbituricacid;2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-(1-cyclohexen-1-yl)-1,5-dimethyl-;Cyclopan | | CAS: | 56-29-1 | | MF: | C12H16N2O3 | | MW: | 236.27 | | EINECS: | 200-264-9 | | Product Categories: | | | Mol File: | 56-29-1.mol |  |
| | HEXOBARBITAL Chemical Properties |
| Melting point | 145-147° | | Boiling point | 378.73°C (rough estimate) | | density | 1.1623 (rough estimate) | | refractive index | 1.5460 (estimate) | | Fp | 11 °C | | storage temp. | 2-8°C | | pKa | 7.99±0.10(Predicted) | | Water Solubility | 434.7mg/L(25 ºC) | | EPA Substance Registry System | Hexobarbital (56-29-1) |
| | HEXOBARBITAL Usage And Synthesis |
| Description | Hexobarbital, 5-(cyclohexen-1-
yl)-1,5-dimethylbarbituric acid,Mr 236.26. The
acid forms colorless crystals that turn pink on exposure
to light, mp 146 ?C. A 10 % aqueous solution
of the sodium salt, Mr 258.25,
has a pH of 11.5. | | Chemical Properties | White crystals. | | Uses | Medicine (sedative). | | Definition | ChEBI: A member of the class of barbiturates taht is barbituric acid substituted at N-1 by methyl and at C-5 by methyl and cyclohex-1-enyl groups. | | Brand name | Cyclonal sodium;Cyclopan;Dorico soluble;Eviderm;Evipal sodium;Evipanl;Hexanal;Hexanastab oral. | | World Health Organization (WHO) | Hexobarbital is a short-acting barbiturate. See WHO comment for
barbiturates. | | Clinical Use | Methohexital sodium is a short-acting anesthetic
administered intravenously. It is very potent
and has the shortest duration of action
among the barbiturates used. A disturbing factor
is that rather frequently it causes hiccups directly
after injection. Patients are reported to recover
rapidly from anesthesia. Abuse can lead to addiction. | | Synthesis | Hexobarbital sodium is prepared by condensation
of methyl(cyclohexen-1-yl)cyanoacetic
ester with dicyanodiamide to 5-(cyclohexen-
1-yl)-5-methyl-2,6-diimino-3-cyanobarbituric
acid, followed by methylation with dimethyl
sulfate and hydrolysis with 25 % sulfuric acid
. |
| | HEXOBARBITAL Preparation Products And Raw materials |
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