| Company Name: |
Yichang Zhongyitai Trading Co., Ltd.
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0717-6449896 13886658719 |
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root@zhongyitai.com |
| Products Intro: |
Product Name:12(S)-hydroperoxy-5(Z),8(Z),10(E),14(Z)-Eicosatetraenoic acid
CAS:71774-10-2
Purity:98+% Package:100ug
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| Company Name: |
Shanghai EFE Biological Technology Co., Ltd.
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| Tel: |
021-65675885 18964387627 |
| Email: |
info@efebio.com |
| Products Intro: |
Product Name:12(S)-HpETE Lipid Maps MS Standard
CAS:71774-10-2
Purity:98% Package:25μg;50μg;100μg
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| Company Name: |
Shanghai Hongye Biotechnology Co. Ltd
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| Tel: |
400-9205774 |
| Email: |
sales@glpbio.cn |
| Products Intro: |
Product Name:12(S)-HpETE
CAS:71774-10-2
Purity:>98% Package:1mg;10mg;50mg;100mg;
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| Company Name: |
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
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| Tel: |
18818260767 |
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sales@chemegen.com |
| Products Intro: |
Product Name:12(S)-HpETE
CAS:71774-10-2
Purity:98% Package:10 mg;50 mg;100 mg;500 mg;1 g;5 g;10 g
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| Company Name: |
MedBioPharmaceutical Technology Inc
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| Tel: |
021-69568360 18916172912 |
| Email: |
order@med-bio.cn |
| Products Intro: |
Product Name:12(S)-HPETE
CAS:71774-10-2
Purity:98% Package:100ug (solution); 50ug (solution); 250ug (solution); 25ug (solution) Remarks:Medbio
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| | 12(S)-HPETE Basic information |
| Product Name: | 12(S)-HPETE | | Synonyms: | 12S-HYDROPEROXY-5Z,8Z,10E,14Z-EICOSATETRAENOIC ACID;12(S)-HYDROPEROXYEICOSA-5Z,8Z,10E,14Z-TETRAENOIC ACID;12(S)-HPETE;(12S)-12-hydroperoxyicosa-5,8,10,14-tetraenoic acid;(5Z,8Z,10E,12S,14Z)-12-Hydroperoxy-5,8,10,14-icosatetraenoic acid;(5Z,8Z,10E,12S,14Z)-12-Hydroperoxyicosa-5,8,10,14-tetraenoic acid;12(S)-Hydroperoxy-eicosatetraenoic acid;(5Z,8Z,10Z,12S,14Z)-12-Hydroperoxy-5,8,10,14-icosatetraenoic acid | | CAS: | 71774-10-2 | | MF: | C20H32O4 | | MW: | 336.47 | | EINECS: | | | Product Categories: | | | Mol File: | 71774-10-2.mol |  |
| | 12(S)-HPETE Chemical Properties |
| Boiling point | 518.0±50.0 °C(Predicted) | | density | 1.013±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | 0.1 M Na2CO3: 2 mg/ml; DMF: Miscible; DMSO: Miscible; Ethanol: Miscible; PBS pH 7.2: 0.8 mg/ml | | form | Liquid. | | pka | 4.75±0.10(Predicted) |
| | 12(S)-HPETE Usage And Synthesis |
| Description | 12(S)-HpETE is a monohydroperoxy polyunsaturated fatty acid (PUFA) produced by the action of platelet or leukocyte 12-lipoxygenase (12-LO) on arachidonic acid. It activates human blood leukocyte 5-LO, resulting in the synthesis of 5(S)-HETE, leukotriene B4 (LTB4), and 5(S),12(S)-DiHETE. Rat lung metabolizes 12(S)-HpETE to 8,11,12- and 10,11,12-trihydroxyeicostrienoic acids. 12(S)-HpETE is the mediator of many biological functions, including induction of c-fos and c-jun, activation of AP-1, and endothelium-dependent vasoconstriction. It mediates the inhibitory synaptic response to FMRF-amide in Aplysia sensory neurons and inhibits Ca2+/calmodulin-dependent protein kinase II from rat brain cortex. | | Uses | 12(S)-HPETE is a fatty acid and an activator of human blood leukocyte 5-LO. | | Definition | ChEBI: 12(S)-HPETE is the (S)-enantiomer of 12-HPETE. It has a role as a mouse metabolite. It is functionally related to an icosa-5,8,10,14-tetraenoic acid. It is a conjugate acid of a 12(S)-HPETE(1-). It is an enantiomer of a 12(R)-HPETE. |
| | 12(S)-HPETE Preparation Products And Raw materials |
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