- Prednicarbate
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- $0.00 / 1Kg/Bag
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2021-09-29
- CAS:73771-04-7
- Min. Order: 1KG
- Purity: 97%-102%; EPV
- Supply Ability: 50kgs
- Prednicarbate
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- $7.00 / 1KG
-
2019-07-10
- CAS: 73771-04-7
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 100KG
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| | Prednicarbate Basic information |
| Product Name: | Prednicarbate | | Synonyms: | PREDNICARBATE;11β，17，21-Trihydroxypregna-1，4-diene-3，20-dione 17-(ethylcarbonate)-21-propionate;[2-(17-ethoxycarbonyloxy-11-hydroxy-10,13-dimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6h-cyclopenta[a]phenanthren-17-yl)-2-oxo-ethyl] propanoate;Dermatop;HOE-777;Prednitop;Regemt;S-77-0777 | | CAS: | 73771-04-7 | | MF: | C27H36O8 | | MW: | 488.57 | | EINECS: | 277-590-3 | | Product Categories: | Intermediates & Fine Chemicals;Pharmaceuticals;Steroids | | Mol File: | 73771-04-7.mol |  |
| | Prednicarbate Chemical Properties |
| Melting point | 110-112°; mp 183° | | alpha | D20 +63° (c = 0.1 in ethanol) | | Boiling point | 640.7±55.0 °C(Predicted) | | density | 1.25±0.1 g/cm3(Predicted) | | storage temp. | Refrigerator | | solubility | Practically insoluble in water, freely soluble in acetone and in ethanol (96 per cent), sparingly soluble in propylene glycol. It shows polymorphism (5.9). | | pka | 14.05±0.70(Predicted) | | color | White to Off-White |
| | Prednicarbate Usage And Synthesis |
| Description | Prednicarbate is a potent topical antiinflammatory agent with minimal systemic effects. It is useful in the treatment of cutaneous inflammatory disorders such as eczema and psoriasis. | | Description | Prednicarbate is a synthetic corticosteroid and a derivative of prednisolone . It has anti-inflammatory activity comparable to that of desoximetasone in various murine models when administered topically but lacks activity when administered subcutaneously. Topical administration of prednicarbate (2 drops of a 0.1% solution per day) induces wound healing in hairless mice. Formulations containing prednicarbate have been used to treat chronic hand eczema. | | Chemical Properties | White or almost white, crystalline powder. | | Originator | Hoechst AG (W. Germany) | | Uses | Topical anti-inflammatory agent. Glucocorticoid.
Prednicarbate (Dermatop E) is a synthetic nonfluorinated topical corticosteroid. | | Definition | ChEBI: Prednicarbate is a corticosteroid hormone. | | Indications | Prednicarbate (Dermatop E) is a synthetic nonfluorinated topical corticosteroid. | | Brand name | Dermatop (Sanofi Aventis). | | General Description | Prednicarbate, 17-[(ethoxycarbonyl)oxy]-11β-hydroxy-21-(1-oxopropoxy)pregna-1,4-diene-3,20-dione, is a prednisolone derivative with a C21 propionateester and a C17 ethyl carbonate group. It is availablefor use only in a 0.1% topical cream. Prednicarbate is amedium-potency GC. |
| | Prednicarbate Preparation Products And Raw materials |
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