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N-Carbethoxyphthalimide

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CAS:22509-74-6
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CAS:22509-74-6
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N-Carbethoxyphthalimide manufacturers

  • N-Carbethoxyphthalimide
  • N-Carbethoxyphthalimide pictures
  • $100.00 / 25kg
  • 2023-01-31
  • CAS:22509-74-6
  • Min. Order: 1kg
  • Purity: 99%
  • Supply Ability: 50000KG/month
N-Carbethoxyphthalimide Basic information
Product Name:N-Carbethoxyphthalimide
Synonyms:1,3-dihydro-1,3-dioxo-2h-isoindole-2-carboxylicaciethylester;1,3-dioxo-2-isoindolinecarboxylicaciethylester;N-(Carboethoxy)phthalimide~Nefkens;Ethyl phthalimidocarboxylate;N-Ethoxycarbonylphthalimide [for Peptide synthesis];N-Carbethoxyphthalimide, 98+%;N-Carbethoxyphthalimide, 99+%;N-Ethoxycarbonylphthalimide, Ethyl 1,3-dioxo-2-isoindolinecarboxylate, Ethyl phthalimide-N-carboxylate
CAS:22509-74-6
MF:C11H9NO4
MW:219.19
EINECS:245-048-5
Product Categories:Biochemistry;N-Substituted Maleimides, Succinimides & Phthalimides;N-Substituted Phthalimides;Peptide Synthesis;Protection & Derivatization Reagents (for Synthesis);Protective Reagents (Peptide Synthesis);Synthetic Organic Chemistry
Mol File:22509-74-6.mol
N-Carbethoxyphthalimide Structure
N-Carbethoxyphthalimide Chemical Properties
Melting point 90-92 °C(lit.)
Boiling point 360°C (rough estimate)
density 1.3219 (rough estimate)
vapor pressure 0.003-0.006Pa at 20-25℃
refractive index 1.4950 (estimate)
storage temp. Inert atmosphere,2-8°C
solubility DMSO (Slightly), Methanol (Slightly)
pka-3.02±0.20(Predicted)
form Crystalline Powder
color White
Water Solubility insoluble
BRN 196340
InChIKeyVRHAQNTWKSVEEC-UHFFFAOYSA-N
LogP1.1 at 20℃ and pH6.6-6.9
CAS DataBase Reference22509-74-6(CAS DataBase Reference)
NIST Chemistry Reference2H-isoindole-2-carboxylic acid, 1,3-dihydro-1,3-dioxo-, ethyl ester(22509-74-6)
EPA Substance Registry System2H-Isoindole-2-carboxylic acid, 1,3-dihydro-1,3-dioxo-, ethyl ester (22509-74-6)
Safety Information
Hazard Codes Xn
Risk Statements 22-36/37/38-20/21/22
Safety Statements 22-24/25-36/37/39-26-36
WGK Germany 3
RTECS NR3459500
10
TSCA Yes
HazardClass IRRITANT
HS Code 29251995
MSDS Information
ProviderLanguage
Ethyl phthalimidocarboxylate English
SigmaAldrich English
ACROS English
ALFA English
N-Carbethoxyphthalimide Usage And Synthesis
Chemical PropertiesWhite crystalline powder
UsesN-Carbethoxyphthalimide is used in the synthetic preparation of a novel dual binders as potent, selective, and orally bioavailable tankyrase inhibitors.
Purification MethodsCrystallise the imide from toluene/pet ether (or *benzene/pet ether). It is partly soluble in Et2O, *benzene and CHCl3. [Heller & Jacobsohn Chem Ber 54 1112 1921, Beilstein 21/10 V 428.]
Tag:N-Carbethoxyphthalimide(22509-74-6) Related Product Information
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