| | CANNABINOL Basic information |
| Product Name: | CANNABINOL | | Synonyms: | 3-Amyl-1-hydroxy-6,6,9-trimethyl-6H-dibenzo(b,d)pyran;6,6,9-Trimethyl-3-pentyl-6H-benzo[c]chromen-1-ol;6H-Dibenzo[b,d]pyran-1-ol, 6,6,9-trimethyl-3-pentyl-;cannabinolmethanolsolution;CBN;NSC 134455;CANNABINOL;6,6,9-TRIMETHYL-3-PENYL-6H-DIBENZO(B,D)PURAN-1-OL | | CAS: | 521-35-7 | | MF: | C21H26O2 | | MW: | 310.43 | | EINECS: | 689-788-0 | | Product Categories: | Aromatics;Heterocycles;Intermediates & Fine Chemicals;Metabolites & Impurities;CA - CGDrugs of Abuse;CannabiolForensic and Veterinary Standards;Alphabetic;C;Chemical Structure;Drugs&Metabolites;Solutions;Cannabinoid receptor;Neurochemicals;Pharmaceuticals | | Mol File: | 521-35-7.mol |  |
| | CANNABINOL Chemical Properties |
| Melting point | 76-77° | | Boiling point | bp0.05 185° | | density | 1.0865 (rough estimate) | | refractive index | 1.4900 (estimate) | | Fp | 11 °C | | storage temp. | 2-8°C | | pka | 9.40±0.40(Predicted) | | Stability: | Stable. Combustible. Incompatible with strong oxidizing agents. | | EPA Substance Registry System | Cannabinol (521-35-7) |
| | CANNABINOL Usage And Synthesis |
| Chemical Properties | thin platelets | | Uses | A metabolite of Tetrahydrocannabinol (T293200). A psychoactive substance cannabinoid that acts as a weak agonist of the CB1 and CB2 receptors. | | Definition | ChEBI: Cannabinol is a dibenzopyran. | | General Description | Leaflets. | | Reactivity Profile | CANNABINOL is an alcohol. Flammable and/or toxic gases are generated by the combination of alcohols with alkali metals, nitrides, and strong reducing agents. They react with oxoacids and carboxylic acids to form esters plus water. Oxidizing agents convert them to aldehydes or ketones. Alcohols exhibit both weak acid and weak base behavior. They may initiate the polymerization of isocyanates and epoxides. | | Fire Hazard | Flash point data for CANNABINOL are not available, but CANNABINOL is probably combustible. | | Biological Activity | CB 1 and CB 1 receptor agonist (K i values are 126 and 211 nM respectively). Inhibits adenylyl cyclase (EC 50 values are 120 and 261 nM for CB 1 and CB 2 receptors respectively) and suppresses immune cell function. Major constituent of cannabis; displays little or no psychotropic activity. | | Purification Methods | Cannabinol crystallises from pet ether and sublimes in a vacuum. [Meitzer et al. Synthesis 985 1981, Beilstein 17 II 151, 17 III/IV 1652.] |
| | CANNABINOL Preparation Products And Raw materials |
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