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| | Ethyltriphenylphosphonium bromide Basic information |
| | Ethyltriphenylphosphonium bromide Chemical Properties |
| Melting point | 203-205 °C(lit.) | | Boiling point | 240℃[at 101 325 Pa] | | density | 1.38[at 20℃] | | vapor pressure | 0-0.1Pa at 20-25℃ | | Fp | 200 °C | | storage temp. | Inert atmosphere,Room Temperature | | solubility | 174g/l soluble | | form | Crystalline Powder | | color | White to off-white | | Water Solubility | 120 g/L (23 ºC) | | Sensitive | Hygroscopic | | BRN | 3599630 | | InChIKey | JHYNXXDQQHTCHJ-UHFFFAOYSA-M | | LogP | -0.69--0.446 at 35℃ | | CAS DataBase Reference | 1530-32-1(CAS DataBase Reference) | | EPA Substance Registry System | Phosphonium, ethyltriphenyl-, bromide (1530-32-1) |
| | Ethyltriphenylphosphonium bromide Usage And Synthesis |
| Chemical Properties | White to off-white crystalline powder | | Uses | suzuki reaction | | Uses | Ethyltriphenylphosphonium Bromide (ETPB) is a phase transfer catalyst, used to accelerate the cure of phenolic-based epoxy resins, certain fluoroelastomer resins and thermosetting powder coatings. It is also used as catalysts in the synthesis of certain organic compounds and as a pharmaceutical intermediate.
- Ethyltriphenylphosphonium bromide acts as a reactant in the synthesis of D-amino acids from L-cysteine-derived thiazolidines, Leiodolide A through aldol reactions and Horner-Wadsworth-Emmons olefination.
- It is also used in the preparation of cycloalkanoindolines through diastereoselective intramolecular inimo-ene reactions.
- it is used as a reagent in solid-state metathesis polycondensation to prepare alkyl-dipropenylthiophene monomers.
- Mizoroki-Heck cyclization and cascading Tsuji-Trost cyclization reactions.
| | Uses | PTC catalyst | | Uses | Ethyltriphenylphosphonium Bromide is used as a wittig reagent. Ethyltriphenylphosphonium Bromide and other phosphonium salts show antiviral activity. | | Flammability and Explosibility | Not classified | | Purification Methods | Recrystallise it from H2O and dry it in high vacuum at 100o. IR has bands at 1449, 1431 and 997cm-1 . [Wittig & Wittenberg Justus Liebigs Ann Chem 606 1 1957, Bergmann & Dusza J Org Chem 23 1245 1958, Beilstein 16 IV 982.] |
| | Ethyltriphenylphosphonium bromide Preparation Products And Raw materials |
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