| Company Name: |
Hangzhou Sage Chemical Co., Ltd.
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| Tel: |
+86057186818502 13588463833 |
| Email: |
info@sagechem.com |
| Products Intro: |
Product Name:2-ButenaMide, N-[1-[(diMethylaMino)carbonyl]propyl]-N-ethyl-
CAS:6168-76-9
Purity:98% Package:1g;5g;100g;Bulk
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| Company Name: |
LGC Science (Shanghai) Ltd.
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| Tel: |
17717235263 |
| Email: |
cindy.yang@lgcgroup.com |
| Products Intro: |
Product Name:Crotethamide
CAS:6168-76-9
Purity:具体纯度详见COA，官网可下载COA样本: Package:250mg;2.5g
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| | crotetamide Basic information |
| | crotetamide Chemical Properties |
| Melting point | <25 °C | | Boiling point | bp0.03 132-134° | | density | 0.986±0.06 g/cm3(Predicted) | | storage temp. | -20°C Freezer | | solubility | Chloroform (Sparingly), Ethyl Acetate (Slightly), Methanol (Slightly) | | pka | -0.74±0.70(Predicted) | | form | Oil | | color | Colourless to Light Yellow |
| | crotetamide Usage And Synthesis |
| Chemical Properties | Pale Yellow Oil | | Originator | Micorene,Geisy | | Uses | Analgesic; combination as respiratory stimulant. | | Definition | ChEBI: Crotetamide is an organooxygen compound and an organonitrogen compound. It is functionally related to an alpha-amino acid. | | Manufacturing Process | 2-Clorobutiric acid dimethyl amide is dissolved in absolute benzene and
heated to 110°-120°C with ethylamine in the autoclave. After cooling the
ethylamine hydrochloride is filtered off, then the benzene solution is treated
with water and freed from any dissolved ethylamine hydrochloride by means
of potassium lye. After distillation of the benzene the 2-ethylaminobutyric acid
dimethyl amide is rectified in vacuum.
2-Ethylaminobutyric acid dimethyl amide is dissolved in absolute ether, then
the mixture is well cooled and treated drowsy under stirring with crotonic acid
chloride. After a stirring reaction mixture is filtered and residue obtained is
dissolved in water and treated by potassium hydroxide. The remaining product
is finally rectified in high vacuum to give 2-(N-ethyl-crotonylamido)butyric
acid dimethyl amide. | | Therapeutic Function | Respiratory stimulant |
| | crotetamide Preparation Products And Raw materials |
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