| Company Name: |
Energy Chemical
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| Tel: |
021-58432009 400-005-6266 |
| Email: |
marketing@energy-chemical.com |
| Products Intro: |
Product Name:Dimethisterone
CAS:79-64-1
Purity:NULL Package:100mg;10mg Remarks:NULL
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| | DIMETHISTERONE Basic information |
| Product Name: | DIMETHISTERONE | | Synonyms: | DIMETHISTERONE;17β-Hydroxy-6α-methyl-17-(1-propynyl)androst-4-en-3-one;6α,21-Dimethylethisterone;Lutogan;Ovin;P 5048;Secrosteron;6α-Methyl-17-(1-propynyl)testosterone | | CAS: | 79-64-1 | | MF: | C23H32O2 | | MW: | 340.5 | | EINECS: | 201-215-4 | | Product Categories: | | | Mol File: | 79-64-1.mol |  |
| | DIMETHISTERONE Chemical Properties |
| Melting point | 102° | | alpha | D20 +10° (c = 1 in chloroform) | | Boiling point | 416.28°C (rough estimate) | | density | 1.0555 (rough estimate) | | refractive index | 1.4480 (estimate) | | pka | 13.03±0.70(Predicted) | | EPA Substance Registry System | Dimethisterone (79-64-1) |
| | DIMETHISTERONE Usage And Synthesis |
| Originator | Oracon,Mead Johnson,US,1965 | | Uses | Dimethisterone-d3 is the labeled analogue of Dimethisterone (D460430), an oral contraceptive steroid. | | Definition | ChEBI: Dimethisterone is a 3-hydroxy steroid. It has a role as an androgen. | | Manufacturing Process | A solution of a Grignard reagent, employing 1-propyne (8 grams) was
prepared. To this reagent there was added the 3,3 ethylenedioxy derivative (4
grams) of 6-α-methylandrost-4-ene-3,17-dione in tetrahydrofuran (100 ml),
and the mixture heated under reflux for 3 hours. After decomposition of the
complex with aqueous ammonium chloride, the product was isolated with
ether and treated with 90% acetic acid (50 ml) for 30 minutes at 100°C. The
product obtained by pouring the mixture into water and extracting with ether
was crystallized from aqueous methanol. 17β-Hydroxy-6α-methyl-17α-(prop-
1-ynyl)androst-4-en-3-one formed plates MP 99° to 102°C. | | Therapeutic Function | Progestin |
| | DIMETHISTERONE Preparation Products And Raw materials |
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