- Toloxatone USP/EP/BP
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- $1.10 / 1g
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2021-07-27
- CAS:29218-27-7
- Min. Order: 1g
- Purity: 99.9%
- Supply Ability: 100 Tons min
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| | Toloxatone Basic information |
| Product Name: | Toloxatone | | Synonyms: | 2-OXAZOLIDINONE, 5-(HYDROXYMETHYL)-3-(3-METHYLPHENYL)-;Toloxatone;ToloxatonetoloxatonetoloxatoneToloxatone;5-Hydroxymethyl-3-(3-methylphenyl)oxazolidin-2-one;Humoryl;MD-69276;Perenum;5-(Hydroxymethyl)-3-(m-tolyl)oxazolidin-2-one | | CAS: | 29218-27-7 | | MF: | C11H13NO3 | | MW: | 207.23 | | EINECS: | 249-522-2 | | Product Categories: | | | Mol File: | 29218-27-7.mol |  |
| | Toloxatone Chemical Properties |
| Melting point | 76° | | Boiling point | 358.9±21.0 °C(Predicted) | | density | 1.245±0.06 g/cm3(Predicted) | | storage temp. | Inert atmosphere,2-8°C | | solubility | DMSO: >10mg/mL | | pka | 14.05±0.10(Predicted) | | form | solid |
| Hazard Codes | Xn | | Risk Statements | 22 | | RIDADR | 3249 | | WGK Germany | 3 | | RTECS | RQ2867500 | | HazardClass | 6.1(b) | | PackingGroup | III | | Toxicity | LD50 orally in mice (mg/kg): 1850 (Fauran); also reported as 1500 (Raynaud) |
| | Toloxatone Usage And Synthesis |
| Description | Toloxatone is a selective, reversible and competitive inhibitor of type A
monoamine oxidase (MAO-A) which shows clinical utility as an antidepressant. It
is reportedly free of the "cheese effect" in man, possibly due to the reversible
nature of its inhibitory effect on intestinal MAO-A in the presence of high
concentrations of tyramine. | | Originator | Delalande (France) | | Uses | Toloxatone is a monoamine oxidase-A (MAO-A) inhibitor. | | Definition | ChEBI: 5-(hydroxymethyl)-3-(3-methylphenyl)-1,3-oxazolidin-2-one is a member of the class of oxazolidinones that is 5-(hydroxymethyl)-1,3-oxazolidin-2-one substituted by a 3-methylphenyl group at position 3. It is a member of toluenes, an oxazolidinone and a primary alcohol. | | Brand name | HUMORYL |
| | Toloxatone Preparation Products And Raw materials |
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