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| | 3-Methoxybenzamide Basic information |
| Product Name: | 3-Methoxybenzamide | | Synonyms: | 3-methoxy-benzamid;Benzamide, 3-methoxy-;M-ANISAMIDE;3-ANISAMIDE;3-METHOXYBENZAMIDE;M-METHOXYBENZAMIDE;3-MBA;FtsZ,ADPRT,PARP,3 Methoxybenzamide,microtuber,Bacterial,3-Methoxybenzamide,inhibit,poly ADP ribose polymerase,Inhibitor,3Methoxybenzamide | | CAS: | 5813-86-5 | | MF: | C8H9NO2 | | MW: | 151.16 | | EINECS: | 227-379-7 | | Product Categories: | Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts | | Mol File: | 5813-86-5.mol |  |
| | 3-Methoxybenzamide Chemical Properties |
| Melting point | 132.5-135.5 °C (lit.) | | Boiling point | 280.0±23.0 °C(Predicted) | | density | 1.143±0.06 g/cm3(Predicted) | | storage temp. | Sealed in dry,Room Temperature | | solubility | DMF: 30 mg/ml,DMSO: 30 mg/ml,DMSO:PBS (pH 7.2) (1:1): 0.50 mg/ml,Ethanol: 1 mg/ml | | form | A crystalline solid | | pka | 15.81±0.50(Predicted) | | Water Solubility | Soluble in water. | | BRN | 2206857 | | InChI | InChI=1S/C8H9NO2/c1-11-7-4-2-3-6(5-7)8(9)10/h2-5H,1H3,(H2,9,10) | | InChIKey | VKPLPDIMEREJJF-UHFFFAOYSA-N | | SMILES | C(N)(=O)C1=CC=CC(OC)=C1 | | CAS DataBase Reference | 5813-86-5(CAS DataBase Reference) |
| WGK Germany | 3 | | RTECS | CV5463333 | | HS Code | 2924297099 |
| | 3-Methoxybenzamide Usage And Synthesis |
| Uses | 3-Methoxybenzamide is act as an inhibitor of ADP-ribosyltransferase. It is also a weak inhibitor of the essential bacterial cell division protein FtsZ. Alkyl derivatives of 3-Methoxybenzamide are potent antistaphylococcal compounds with suboptimal drug-like properties. | | Biological Activity | 3-Methoxybenzamide (3-MBA), an inhibitor of ADP-ribosyltransferase (ADPRTs) and PARP, inhibits cell division in Bacillus subtilis, leading to filamentation and eventually lysis of cells. 3-Methoxybenzamide (3-MBA) enhances in vitro plant growth, microtuberization, and transformation efficiency of blue potato (Solanum tuberosum L. subsp. andigenum). | | in vitro | 3-Methoxybenzamide (0-30 mM) affects septation via the FtsZ system during both vegetative growth and sporulation. 3-Methoxybenzamide (3 MB; 0.2 to 0.6 mM) significantly increaseS the growth and microtuber formation of in vitro propagated plants. |
| | 3-Methoxybenzamide Preparation Products And Raw materials |
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