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ChemicalBook >> CAS DataBase List >> Amifostine

Amifostine

Amifostine price.
  • $34 - $2000
  • Product name: Amifostine
  • CAS: 20537-88-6
  • MF: C5H15N2O3PS
  • MW: 214.22
  • EINECS:633-786-4
  • MDL Number:MFCD00233058
  • Synonyms:γphos;Fosteamine;2-(3-Aminopropyl)aminoethyl phosphorothioate, WR2721;Ethiotas;S-2-[(3-Aminopropyl)amino]ethanethiol dihydrogen phosphate ester;Amifostine,2-(3-Aminopropyl)aminoethyl phosphorothioate, WR2721;AMifostine anhydrous;AMifostine(Ethiofos)
14 prices
Selected condition:
Brand
  • aablocks
  • AK Scientific
  • AvaChem
  • ChemScene
  • Medical Isotopes, Inc.
  • Tocris
  • TRC
Package
  • 100
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 1g
  • 5g
  • Manufactureraablocks
  • Product numberAA0029YA
  • Product descriptionAmifostine 98%(HPLC)
  • Packaging5mg
  • Price$53
  • Updated2021-12-16
  • Buy
  • Manufactureraablocks
  • Product numberAA0029YA
  • Product descriptionAmifostine 98%(HPLC)
  • Packaging10mg
  • Price$88
  • Updated2021-12-16
  • Buy
  • Manufactureraablocks
  • Product numberAA0029YA
  • Product descriptionAmifostine 98%(HPLC)
  • Packaging25mg
  • Price$168
  • Updated2021-12-16
  • Buy
  • Manufactureraablocks
  • Product numberAA0029YA
  • Product descriptionAmifostine 98%(HPLC)
  • Packaging50mg
  • Price$318
  • Updated2021-12-16
  • Buy
  • Manufactureraablocks
  • Product numberAA0029YA
  • Product descriptionAmifostine 98%(HPLC)
  • Packaging100mg
  • Price$472
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberH037
  • Product descriptionAmifostine
  • Packaging5mg
  • Price$34
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number2611
  • Product descriptionAmifostine
  • Packaging100mg
  • Price$129
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number2611
  • Product descriptionAmifostine
  • Packaging1g
  • Price$259
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number2611
  • Product descriptionAmifostine
  • Packaging5g
  • Price$790
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-2875
  • Product descriptionAmifostine ≥98.0%
  • Packaging10mg
  • Price$65
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-2875
  • Product descriptionAmifostine ≥98.0%
  • Packaging50mg
  • Price$272
  • Updated2021-12-16
  • Buy
  • ManufacturerMedical Isotopes, Inc.
  • Product number6335
  • Product descriptionAmifostine
  • Packaging50mg
  • Price$2000
  • Updated2021-12-16
  • Buy
  • ManufacturerTocris
  • Product number6655
  • Product descriptionAmifostine
  • Packaging100
  • Price$102
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberA576810
  • Product descriptionAmifostine
  • Packaging100mg
  • Price$55
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA0029YA Amifostine 98%(HPLC) 5mg $53 2021-12-16 Buy
aablocks AA0029YA Amifostine 98%(HPLC) 10mg $88 2021-12-16 Buy
aablocks AA0029YA Amifostine 98%(HPLC) 25mg $168 2021-12-16 Buy
aablocks AA0029YA Amifostine 98%(HPLC) 50mg $318 2021-12-16 Buy
aablocks AA0029YA Amifostine 98%(HPLC) 100mg $472 2021-12-16 Buy
AK Scientific H037 Amifostine 5mg $34 2021-12-16 Buy
AvaChem 2611 Amifostine 100mg $129 2021-12-16 Buy
AvaChem 2611 Amifostine 1g $259 2021-12-16 Buy
AvaChem 2611 Amifostine 5g $790 2021-12-16 Buy
ChemScene CS-2875 Amifostine ≥98.0% 10mg $65 2021-12-16 Buy
ChemScene CS-2875 Amifostine ≥98.0% 50mg $272 2021-12-16 Buy
Medical Isotopes, Inc. 6335 Amifostine 50mg $2000 2021-12-16 Buy
Tocris 6655 Amifostine 100 $102 2021-12-16 Buy
TRC A576810 Amifostine 100mg $55 2021-12-16 Buy

Properties

Melting point :160-1610C
Boiling point :441.7±51.0 °C(Predicted)
Density :1.367±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :Soluble in Water.
form :powder
pka :1.28±0.10(Predicted)
color :White
Water Solubility :Soluble to 100 mM in water
Stability :Stable for 1 year from date of purchase as supplied. Solutions in distilled water may be stored at -20° for up to 3 months.
CAS DataBase Reference :20537-88-6(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P330 Rinse mouth.
P501 Dispose of contents/container to..…

Description

Amifostine, an organic thiophosphate, was introduced for the reduction of cisplatin-induced renal toxicity in patients with advanced ovarian cancer. It is also a radio-protective agent. Amifostine is a prodrug which is rapidly dephosphorylated, preferentially in non-tumor tissues to the active thiol. This agent binds to chemotherapeutic drugs and free radicals released by radiotherapy. The protective effect of amifostine was observed in a wide range of normal organs including bone marrow and gastrointestinal mucosa without interfering with the anti-tumor effect of chemohadiotherapy, indicating an increased therapeutic index for existing cancer treatment. Amifostine is also being evaluated as a cytoprotective in other types of tumors including lung, breast, head and neck cancers. It was reported to be a potent mucolytic with potential in cystic fibrosis.

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