3-phenylpropyl acrylate synthesis
- Product Name:3-phenylpropyl acrylate
- CAS Number:85909-41-7
- Molecular formula:C12H14O2
- Molecular Weight:190.24
![[3-(allyloxy)propyl]benzene](/CAS/GIF/93981-51-2.gif)
93981-51-2
1 suppliers
inquiry
85909-41-7
1 suppliers
inquiry
Yield:85909-41-7 90%
Reaction Conditions:
with tert.-butylhydroperoxide;[bis(acetoxy)iodo]benzene;magnesium acetate in decane;butyl butyrate at 0;chemoselective reaction;
Steps:
4.2. General procedure for the DIB/TBHP protocol
General procedure: o a solution of the substrate in n-butyl butanoate was added DIB (1-1.5 equiv) and Mg(OAc)2·4H2O (1 equiv) at 0 °C. The resulting suspension was vigorously stirred and a solution of TBHP (5 M in decane, 3-6 equiv) was added. The solution was further stirred overnight at 0 °C (total consumption of starting material as indicated by TLC analysis) and then filtered. Diethyl ether was added to the filtrate (5 mL) and the solution was washed with water (5 mL). The solution was dried (MgSO4), evaporated and the residue was purified by flash column chromatography on silica gel using gradient or isocratic elution.
References:
Sastraruji, Thanapat;Pyne, Stephen G.;Ung, Alison T. [Tetrahedron,2012,vol. 68,# 2,p. 598 - 602] Location in patent:experimental part
122-97-4
384 suppliers
$6.00/25g
85909-41-7
1 suppliers
inquiry
122-97-4
384 suppliers
$6.00/25g
625-36-5
358 suppliers
$45.00/5g
85909-41-7
1 suppliers
inquiry
78987-69-6
0 suppliers
inquiry