ChemicalBook CAS DataBase List 4-Chloro-2-nitroaniline

4-Chloro-2-nitroaniline synthesis

13synthesis methods

Product Name:4-Chloro-2-nitroaniline
CAS Number:89-63-4
Molecular formula:C6H5ClN2O2
Molecular Weight:172.57

4-Chloro-2-nitrobenzenamine of chlorine.

610-40-2 Synthesis

610-40-2
101 suppliers
$50.00/10g

89-63-4
8 suppliers
$13.00/50g

Yield:89-63-4 90%

Reaction Conditions:

with sodium tetrahydroborate in ethanol;water at 20; for 4 h;Green chemistry;

Steps:

4.5 General procedure for the reduction of nitro aromatic using starch-crt(at)Au
General procedure: To a flask containing nitroarene (0.5 mmol), starch-crt(at)Au (0.1 mol%, 25 mg) and NaBH₄ (2.5 mmol, 45 mg), 2 mL of H₂O:EtOH (1:1) was added. Reaction mixture was stirred at room temperature for the appropriate reaction times (see Tables 2 and 3). Progress of the reactions were monitored by GC, TLC and or ¹H NMR. After completion of the reaction, the crude product was extracted with ethyl acetate (3 × 5 mL). The solvent was evaporated and the residue was purified using column or plate chromatography.

References:

Gholinejad, Mohammad;Dasvarz, Neda;Shojafar, Mohammad;Sansano, José M. [Inorganica Chimica Acta,2019,vol. 495,art. no. 118965]

FullText

88-74-4 Synthesis