ChemicalBook CAS DataBase List 7-Nitroindole

7-Nitroindole synthesis

9synthesis methods

Product Name:7-Nitroindole
CAS Number:6960-42-5
Molecular formula:C8H6N2O2
Molecular Weight:162.15

75-07-0 Synthesis

75-07-0
408 suppliers
$14.00/5mL

88-74-4 Synthesis

88-74-4
8 suppliers
$10.00/1g

6960-42-5
247 suppliers
$10.00/1g

Yield:6960-42-5 90%

Reaction Conditions:

with C₁₄H₂₂B₁₀Br₂FeN₂ in toluene at 20; for 4 h;

Steps:

6 The ferrous complex prepared in Example 1 was used as a catalyst to catalyze the synthesis of indole derivatives:

Toluene (toluene) solution of divalent ferrous complex (0.003mmol) was added to 2-nitroaniline (1mmol), then acetaldehyde (1mmol) was added, and the reaction was carried out at room temperature for 240 minutes. After completion, the concentrated reaction solution was directly passed through a silica gel column Chromatographic separation, drying to the same quality, the corresponding indole derivative C8H6N2O2 (yield 90%)

References:

CN113185444,2021,A Location in patent:Paragraph 0049-0052

6960-45-8 Synthesis