Diethyl fumarate synthesis
- Product Name:Diethyl fumarate
- CAS Number:623-91-6
- Molecular formula:C8H12O4
- Molecular Weight:172.18
496-15-1
424 suppliers
$8.00/10g
87-91-2
441 suppliers
$17.46/25G
120-72-9
610 suppliers
$6.00/25g
623-91-6
276 suppliers
$6.00/25g
Yield:623-91-6 41%
Reaction Conditions:
with methyltrioxorhenium(VII) in toluene at 190; for 70 h;regioselective reaction;
Steps:
2.2. Representative procedure for DODH reactions
General procedure: 1-Phenyl-2-ethanediol (0.32 mmol, 44 mg), MTO (0.032 mmol,8 mg), indoline (0.36 mmol, 34 lL), toluene (1 mL), and dodecane(5 lL) were added to a thick-walled Ace glass tube reactor. Thereactor was placed in a heating mantle bath at 190 °C for 2.5 h while stirring magnetically. After cooling to room temperature,the reaction mixture was filtered and analyzed by GC-MS. ForNMR of Diprophylline (7-(2,3-Dihydroxypropyl)-3,7-dihydro-1,3-dimethyl-1H-purine-2,6-dione), mucic acid (tetrahydroxyadipicacid), and inositol, a 100 μL aliquot of reaction mixture was withdrawn.To this mixture CDCl3 and 2 μL DMSO as internal standardfor NMR analysis was added. The product was identified and quantifiedby 1H NMR spectroscopy and by comparison with an authenticsample.
References:
Jefferson, Alana;Srivastava, Radhey S. [Polyhedron,2019,vol. 160,p. 268 - 271]
87-91-2
441 suppliers
$17.46/25G
623-91-6
276 suppliers
$6.00/25g
623-73-4
148 suppliers
$26.69/5g
623-91-6
276 suppliers
$6.00/25g
