Polyhexamethylene biguanide hydrochloride---PHMB

Jun 21,2022

PHMB is recognized as the safest and most efficient broad-spectrum antibacterial agent in the 21st century. It is colorless and odorless, with low antibacterial concentration, broad-spectrum and low toxicity, does not cause biological antibodies, has a fast action speed, and has a low amount of foam. Forms a layer of cationic bacteria that lasts for a long time.

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Bactericidal mechanism of action

The guanidine group in PHMB has high activity, which can make the polymer become positively charged and easily adsorbed by all kinds of bacteria and viruses that are negatively charged, thereby inhibiting the splitting function of bacteria and viruses, making them lose their reproductive ability, plus The film formed by the polymer blocks the respiratory passages of the microorganisms, causing the microorganisms to suffocate and die quickly.

Bactericidal Effect

Fast acting on bacteria and viruses

Acts on Gram-positive and Gram-negative bacteria

Acts on pathogens (e.g. E. coli 0157:H7)

Acts on bacteria that are resistant to antibiotics

Acts on enveloped and naked viruses

Application

(1)Used in wet wipes

Its antibacterial effect is mainly by dissolving lipids, changing the permeability of bacterial cell membranes, and causing obstacles to metabolism in bacteria.

(2) Special sterilizers for households and public places

(3)Used in aquaculture

This product can quickly kill harmful bacteria such as Gram-negative bacteria, Floating Vibrio, Vibrio parahaemolyticus and Vibrio alginolyticus in seawater.

(4) Disinfectant for skin and wound surface

The product can also be used for disinfection of air, walls and floors in wards.

(5)Used in women's lotion

The lotion and gel disinfectant made by this product can be used for bacterial, fungal, trichomoniasis, senile and non-specific inflammation, cervicitis and other diseases.

(6)Used in hand sanitizer

It can form a colorless and transparent invisible film on the hand to maintain a long-term anti-bacterial and bactericidal effect.

(7)Used in the textile industry and sanitary napkins, sanitary pads, baby diapers and other products

The product can develop antibacterial textiles, such as towels, underwear, baby clothes, bedding and so on.

(8)Used in cleaning agent

The product has the advantages of being water-soluble, non-toxic, colorless, odorless, non-corrosive, non-fading, non-irritating to skin and mucous membranes, and has a long validity period.

(9) Used in beer, beverage and food processing industries

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    PHMB is best known for its broad-spectrum antimicrobial and antifungal activity. It is the standard of care for treatment of Acanthamoeba keratitis and an ingredient in multipurpose contact lens solutions, such as Renu (Bauch & Lomb, Roches

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Poly(hexamethylenebiguanide)hydrochloride manufacturers