Active Pharmaceutical Ingredients (API), popularly speaking, are the raw materials of medicines, only pharmaceutical raw materials are processed into pharmaceutical preparations , can they become medicines available for clinical use, so drugs we usually eat are the finished drugs through processing. Active Pharmaceutical Ingredients based on its sources can be divided into two major categories ,including chemical synthetic drugs and natural chemical drugs. Chemical synthetic drugs can be divided into organic synthetic drugs and inorganic synthetic drugs. Inorganic synthetic drugs are inorganic compounds ( very few is element), such as aluminum hydroxide, magnesium trisilicate which are used for the treatment of gastric and duodenal ulcers ; organic synthetic drugs are mainly composed of drugs made by basic organic chemical raw materials, through a series of organic chemical reactions (such as aspirin, chloramphenicol, caffeine, etc.). Natural chemical drugs ,based on its sources,can be divided into two categories including biochemical drugs and plant chemical drugs. Antibiotics are generally made by the microbial fermentation, which belongs to the biochemistry category. A variety of semi-synthetic antibiotics occurs in recent years,which are biosynthesis and chemical synthesis combining products.Among active Pharmaceutical Ingredients, the organic synthetic drugs varieties, yields and values have the largest proportion,which are the main pillars of the chemical and pharmaceutical industries. The quality of active Pharmaceutical Ingredients decides whether the formulation is good or bad , so its quality standards are very strict ,countries in the world have developed national pharmacopoeia standards and strict quality control methods for its widely used active Pharmaceutical ingredients.
OMadacycline: Mechanism, Bioactivity and Chemical and Toxicological Studies
Omadacycline is a novel antibacterial agent of the tetracycline family, which is currently under clinical development as both intravenous and oral formulations. This new tetracycline has sh
Jan 3,2023 APIOrnidazole:Uses,Mechanism,Dosage,Side effects
Ornidazole is an antibiotic used to treat protozoan infections.A synthetic nitroimidazole, it is commercially obtained from an acid-catalyzed reaction between 2-methyl-5-nitroimidazole and epichlorohy
Dec 29,2022 APIWhat is Daptomycin Used for?
Daptomycin is an antibiotic used to treat serious bacterial infections. It works by stopping the growth of bacteria.This medication is not recommended for use in children younger than 12 months due to
Dec 29,2022 APIEstradiol valerate:Effect,Side effects,
Estradiol valerate is used in hormone therapy for menopausal symptoms and low estrogen levels, hormone therapy for transgender people, and in hormonal birth control.It is also used in the treatment of
Dec 27,2022 APIJosamycin:Uses,Pharmacodynamics,Toxicity,Preparation
The Josamycin, with the CAS No: 16846-24-5, is also known as 3-Acetate 4B-(3-Methylbutanoate) leucoMycin V. This chemical’s molecular formula is C42H69NO15 and molecular weight is 827.99. It belongs t
Dec 27,2022 APILevomefolate calcium:Benefites,uses,deficiency
Levomefolate calcium is an organic calcium salt,it has a role as an antidepressant.Levomefolate calcium is the active metabolic form of folates in the body.
Dec 26,2022 APIAbout the Uses and Side effects of Fasudil hydrochloride
Fasudil hydrochloride is a potent Rho-kinase inhibitor and vasodilator. Since it was discovered, it has been used for the treatment of cerebral vasospasm, which is often due to subarachnoid hemorrhag
Dec 26,2022 API3-isopropylphenol: Application, Chemicaland And Toxicological studies
The 3-isopropylphenol, is also known as 3-isopropylbenzenesulfonyl chloride. It belongs to the Phenolic compound and as a ingredient of disinfectants.
Dec 26,2022 APICetuximab: Bioactivity, Drug resistance, Safety and toxicological studies
Cetuximab is a human IgG1 monoclonal antibody that inhibits epidermal growth factor receptor , with a Kd of 0.201 nM for EGFR by SPR and has potent antitumor activity.
Dec 26,2022 APIWhat is a prednisolone used for?
Prednisolone is a medicine used to treat a wide range of health problems including allergies, blood disorders, skin diseases, inflammation, infections and certain cancers and to prevent organ rejectio
Dec 23,2022 API