Prucalopride: A Selective 5-HT4 Agonist for Gastrointestinal Disorders
Prucalopride treats chronic idiopathic constipation in adults and improves pediatric upper GI symptoms, with favorable efficacy and safety in clinical studies.
Jan 7，2026 API
Thioxanthen-9-one as a Versatile Reagent
Thioxanthen-9-one acts as a triplet photosensitizer for nickel-catalyzed aryl esterification and undergoes reduction via ketyl radical intermediates.
Jan 6，2026 Chemical Reagents
Synthesis and Epoxidation Reaction of 2,4-Difluoro-alpha-(1H-1,2,4-triazolyl)acetophenone
2,4-Difluoro-alpha-(1H-1,2,4-triazolyl)acetophenone is primarily used in the synthesis of the voriconazole racemate.
Jan 6，2026 API
Fluorination Effects of 4-Fluoroacetophenone
4-Fluoroacetophenone, a vital pharmaceutical/fine chemical intermediate, shows fluorination-modulated non-covalent interactions.
Jan 6，2026 Organic Solvents
6,7-Bis-(2-methoxyethoxy)-4(3H)-quinazolinone:synthesis and new application
6,7-Bis-(2-methoxyethoxy)-4(3H)-quinazolinone is a key intermediate for the synthesis of quinazoline-based antitumor drugs such as erlotinib hydrochloride.
Jan 6，2026 Pharmaceutical intermediates
Synthesis and Application of Watermelon Ketone
Watermelon Ketone is a compound developed by Pfizer in 1966 that can affect human olfaction and is used as a fragrance ingredient.
Jan 5，2026 API
1-Naphthaldehyde: Aromatic Aldehyde Intermediate
1-Naphthaldehyde undergoes Lewis acid-modulated ortho photocycloaddition and forms a condensation product that serves as a fluorescent sensor.
Jan 5，2026 Chemical Reagents
4,4'-Oxydiphthalic Anhydride: Dianhydride Monomer and Shape Memory Properties
4,4'-Oxydiphthalic anhydride (ODPA), a key aromatic dianhydride, synthesizes processable (co)polyhydroxyimides and high-temperature shape memory polyimides.
Jan 5，2026 API
1-Aminocyclopropanecarboxylic Acid: Plant Ethylene Precursor and Procognitive Agent
1-Aminocyclopropanecarboxylic acid, mediates ethylene-dependent growth and acts as a procognitive partial agonist at NMDA glycine receptors in rats.
Jan 5，2026 Chemical Materials
Related Research on Pentaerythritol Triacrylate: Applications and Toxicity
Pentaerythritol triacrylate is used in a variety of photoreactive products including inks and coatings. Its related researches were reported.
Jan 5，2026 Carboxylic acids and derivatives