1-Tetralone Derivatives: Anti-Inflammatory, MAO Inhibition, and Asymmetric Synthesis
1-Tetralone derivatives show anti-inflammatory activity via ROS inhibition, and are synthesized asymmetrically with remote quaternary stereocenters.
Jun 23，2025 Chemical Reagents
Ibrexafungerp: Mechanism of Action and Instructions for Use
Ibrexafungerp is the first fourth-generation antifungal drug with a new mechanism of action. It can cover most Candida, Aspergillus, Penicillium multivariate and rare diphasic fungi (such as Histoplas
Jun 20，2025 API
Tropicamide:Class,Uses,Side effects and Administration
Tropicamide is an alkaloid atropine‐derived anticholinergic drug and a non‐selective antagonist of muscarinic acetylcholine (mACh) receptors.
Jun 20，2025 API
Synthesis, Applications, and Toxicological Implications of 9,9-Bis(4-hydroxyphenyl)fluorene
9,9-Bis(4-hydroxyphenyl)fluorene is used in high-performance polymer synthesis but raises concerns as a bisphenol A (BPA) substitute.
Jun 20，2025 Chemical Reagents
LCZ696: A Dual-Action Inhibitor for Hypertension and Heart Failure
LCZ696, an ARNI combining valsartan and AHU377, reduces blood pressure and improves heart function in hypertension and heart failure.
Jun 20，2025 API
Imatinib: Targeted Tyrosine Kinase Inhibitor Transforming Cancer Treatment
Imatinib revolutionizes CML treatment by blocking leukemic cell proliferation, showing durable responses and long-term survival benefits.
Jun 20，2025 API
Deferiprone: Mechanism of action and Preparation method
Deferiprone is used to treat thalassemia that has not responded well to previous chelation therapy and has excessive iron load due to blood transfusion.
Jun 19，2025 Pesticide Intermediates
Fusidic acid:Chemical properties,Uses,Mechanism of action and Side effects
Fusidic acid, a narrow-spectrum antibiotic, is used both systemically and topically to treat primary skin infections, including impetigo.
Jun 19，2025 API
Lithium Sulfide: Properties, Applications, and Advancements in Energy Storage
Lithium sulfide, used in Li-S batteries and solid electrolytes, offers high capacity but faces challenges like high overpotential and slow kinetics.
Jun 19，2025 API
Phentolamine mesylate:Uses, Mechanism of action, Side effects and Acute Toxicity
Phentolamine mesylate is an alpha-adrenergic blocker used to treat hypertensive episodes, diagnose pheochromocytoma, treat norepinephrine administration site reactions, and reverse soft tissue anesthe
Jun 19，2025 API