The synthesis method of Polatuzumab vedotin
Polatuzumab vedotin is an antibody-drug conjugate comprising a monoclonal antibody against CD79b (a B cell receptor component) covalently conjugated to the anti-mitotic cytotoxic agent monomethyl auri
Jan 22,2024 APIHow to synthesize PLX3397 (Pexidartinib)?
?Pexidartinib (PLX3397) is a novel, orally available small molecule tyrosine kinase inhibitor (TKI) with potent and selective activity against the colony-stimulating factor 1 (CSF1) receptor.
Jan 22,2024 InhibitorsN-Fluorobenzenesulfonimide used as fluorine source
N-Fluorobenzenesulfonimide (NFSI) is one of the most popular commercially available N–F reagents.
Jan 22,2024 Organic ChemistryA Research on the toxicity of tert-Butyl acetate
Tert-butyl acetate is a readily available low-cost solvent produced industrially from acetic acid and isobutylene. Its good safety profile makes it suitable for widespread use in catalytic direct amid
Jan 22,2024 Chemical ReagentsZinc Sulfide Nanoparticles: Unique Properties and Potential Applications in Biomedicine
Zinc sulfide nanoparticles possess unique properties for biomedical applications, including wound healing, cancer treatment, and imaging.
Jan 22,2024 APIBromelain: Source, Antimicrobial Efficacy and Therapeutic Applications
Bromelain, a protein found in pineapple stems, has diverse applications in medicine due to its antimicrobial properties, and potential in treating various conditions.
Jan 22,2024 APINano-Platform Carrier Enhances Delivery of Citicoline Sodium for Alzheimer's Disease Treatment
Nano-platform carrier enable targeted delivery of Citicoline sodium to the brain, showing potential as anti-Alzheimer's drug by boosting cholinergic activity and reducing neurodegenerative damage.
Jan 22,2024 APIPhysiologic Basis of Somatotropin and Its Clinical Applications
Somatotropin stimulates ovarian function, improves reproductive outcomes in assisted reproductive technology, and enhances oocyte maturation and endometrial receptivity in in vitro fertilization.
Jan 22,2024 APICarbonization of biowaste with potassium formate to fabricate oxygen-doped porous biochar sorbents
Potassium formate-derived biochars show high sorption capacity for organic pollutants and utilizing micropores. They are easily regenerated and offer promising environmental applications.
Jan 22,2024 APIHydroxylamine Sulfate: Unique Biological Effects and Toxicity Mechanisms Explored
Hydroxylamine sulfate induces methemoglobinemia, causing abnormal hemoglobin production. Mechanisms involve reactive oxygen species and free blood iron. Methylene blue may reduce methemoglobin levels.
Jan 22,2024 API