A semisynthetic pleuromutilin antibiotic: Lefamulin
Lefamulin, a semisynthetic pleuromutilin antibiotic, has been approved by the FDA for IV and oral treatment of community-acquired bacterial pneumonia (CABP) in adults.
Jan 5，2024 APIThe discussion on the polarity of phenol
The sharing of electrons between O and H is unequal, with the electrons more strongly drawn towards O. This results in an overall polar molecule.
Jan 5，2024 Organic Chemistry
Empagliflozin protects the heart against ischemia/reperfusion-induced sudden cardiac death
Empagliflozin is a selective sodium-glucose cotransporter 2 (SGLT2) inhibitor used to lower blood sugar in adults with type 2 diabetes. Empagliflozin also exerts cardioprotective effects independent f
Jan 5，2024 Drugs
A alternative to fossil fuels: 2,5-Furandicarboxylic acid
2,5-Furandicarboxylic acid can replace petroleum-based terephthalic acid to produce biobased plastic polyethylene furan dicarboxylate (PEF) due to the similarity in its functional group with terephtha
Jan 5，2024 Organic Chemistry
Efficacy and safety of Olmesartan Medoxomil in the treatment of hypertension
Olmesartan medoxomil is an orally administered angiotensin II receptor antagonist, selective for the angiotensin II type 1 receptor, which has established antihypertensive efficacy in adults.
Jan 5，2024 Drugs
Hydrocortisone: Clinical applications and Side Effects
Hydrocortisone is a steroid (corticosteroid) medication. It reduces pain, itching and swelling (inflammation) by suppressing the body's immune response.
Jan 5，2024 Drugs
Olivetol: A Promising Compound with Antioxidant and Anticholinergic Properties
Olivetol shows strong antioxidant activity, effective enzyme inhibition, and potential therapeutic applications in oxidative stress-related and acetylcholinesterase-related diseases.
Jan 5，2024 API
Tris Hydrochloride: Versatile Buffer Compound in Biological Research
Tris hydrochloride is is a white crystalline powder used buffer in scientific experiments with adverse effects on neuro-muscular transmission in smooth and cardiac muscle.
Jan 5，2024 API
Mesityl Oxide: A Versatile Compound in Organic Synthesis and Catalysis
Mesityl oxide can be synthesized through acetone, acetic anhydride, and zinc acetate and can act as reactant and catalyst in organic synthesis.
Jan 5，2024 API
S-Adenosyl-L-methionine: A Multi-Faceted Compound in Liver Health and Clinical Application
S-Adenosyl-L-methionine plays a crucial role in transmethylation and has potential in treating liver dysfunction and affective disorders, despite limited bioavailability after oral administration.
Jan 5，2024 API