Abiraterone: mechanism of action, pharmacokinetics and clinical applications

Abiraterone inhibits androgen synthesis via CYP17A to treat mCRPC. Coadministered with prednisone, it improves survival outcomes. Side effects include fatigue and changes in libido.

Sep 4,2023  API

What is Oxalyl chloride?

Chlorine oxalate is a highly toxic substance and a versatile reagent for organic transformation

Sep 4,2023  Chemical pesticides ​

What is hydroxyprogesterone caproate?

Hydroxyprogesterone caproate is a synthetic pregnancy agent and can be used to prevent or delay preterm birth in pregnant women

Sep 1,2023  API

Fulvestrant: a major breakthrough in breast cancer treatment

Fulvestrant, an anti-estrogenic breast cancer treatment, was approved by the US FDA in September 2002 and approved by the European Union in April 2004 for marketing in Europe.

Aug 31,2023  Drugs

Pyridinium p-Toluenesulfonate: properties, applications in organic synthesis and safety

Pyridinium p-Toluenesulfonate is a white crystalline powder with versatile properties. It acts as a mild acid catalyst, facilitating various reactions. Safety precautions should be followed.

Aug 31,2023  API

Benzophenone imine: applications as an ammonia equivalent

Benzophenone imines enables selective primary amine synthesis and N-alkylation through palladium coupling. It also facilitates chiral α-amino acid formation via carbene insertion.

Aug 30,2023  API

2-Methoxy-4-nitroanilin: pharmacokinetics, applications and toxicity

2-Methoxy-4-nitroaniline is a versatile compound used in industries for dyes, pharmaceuticals, and specialty chemicals. It has vibrant colors and participates in diverse reactions.

Aug 30,2023  API

What is Fmoc materials?

Fmoc materials have a stable structure and are widely used in bio-chemicals and pharmaceuticals due to their good stability, low molecular weight, low toxicity, minimal side effect.

Aug 29,2023  Biochemical Engineering

Ascorbyl glucoside: activities and side effects

Ascorbyl glucoside is an antioxidant that treats hyperpigmentation and stimulates collagen production. However, it is important to be cautious of sun sensitivity and potential allergies.

Aug 29,2023  API

2-Hydroxy-2-methylpropiophenone: properties and applications

2-Hydroxy-2-methylpropiophenone is a versatile compound with applications in UV spectroscopy, organic synthesis, photopolymerization, and UV-curable systems.

Aug 29,2023  API
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