Application of 2-ethylhexanol
2-Ethylhexanol is an organic compound with a molecular formula of C8H18O.
Mar 28,2022 APISide effects of Rifampicin
Rifampicin is a most valuable drug for the treatment of tuberculosis, leprosy, other mycobacterial infections, and an expanding range of other bacterial infections.
Mar 25,2022 APIMechanism of action of Pyrazinamide
Pyrazinamide (pyrazine-2-carboxamide) is a first-line antituberculous agent critical to the success of short-course chemotherapy of tuberculosis. It is a derivative of nicotinamide, first synethesized
Mar 25,2022 APISide-effects of Ethambutol
Ethambutol was discovered at Lederle Laboratories in 1961, when randomly selected synthetic compounds were being tested for antituberculosis activity. Chemically, it is dextro-2, 2u-(ethylenediimino)-
Mar 25,2022 APIMechanism of action of Isoniazid
Isoniazid, isonicotinic acid hydrazide (INAH or INH), was discovered independently in 1952 at both Squibb and Roche Laboratories. Animal studies showed that isoniazid was a very potent antituberculosi
Mar 25,2022 APIUse and Safety of Grepafloxacin
Grepafloxacin (OPC-17116) is a broad-spectrum fluoroquinolone with the chemical structure (+)-1-cyclopropyl-6-fluoro-1,4-dihydro-5- methyl-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolone carboxylic acid
Mar 25,2022 APIUses of Temafloxacin
Temafloxacin (6-fluoro-7-piperazino-4-quinolone)was discontinued in June 1992, only five months after gaining marketing approval. This was due to a high rate of reported adverse reactions, including s
Mar 25,2022 APIUses of Fleroxacin
Fleroxacin (Ro 23-6240, AM 833) is different from fluoroquinolones such as ciprofloxacin or ofloxacin, since it is a trifluorinated quinolone, having three fluorine atoms rather than one attached to t
Mar 25,2022 APISide effects of Tosufloxacin
Tosufloxacin was developed by Taisho-Toyama Chemistry (Ozexs) and became commercially available in 1990. It is a newer-generation oral fluoroquinolone with a broad spectrum of activity against Gramneg
Mar 25,2022 APIImipenem: Antimicrobial Activity, Susceptibility, Administration and Dosage, Toxicity, Clinical Uses etc.
In the 1970s, Beecham Research Laboratories identified a carbapenem group, called olivanic acids, which were beta-lactamase inhibitors and broad-spectrum antibiotics (Butterworth et al., 1979).
Mar 25,2022 API