Toxicity of Gatifloxacin

Gatifloxacin is an 8-methoxy fluoroquinolone and is marketed by Bristol Myers Squibb as Tequint. Three formulations are available: oral, ophthalmic, and intravenous. Like other members of this class,

Mar 18,2022  API

The steroid antibiotics---?Fusidic acid

Fusidic acid was developed by Leo Laboratories in Copenhagen and obtained from the fungus Fusidium coccineum.

Mar 18,2022  API

What is Fosfomycin?

Fosfomycin is a phosphoenolpyruvate analogue produced by Streptomyces fradiae and by some Pseudomonas spp., but is now mostly obtained synthetically. It is a broad-spectrum antibiotic with bactericida

Mar 18,2022  API

Ampicillin–Sulbactam: Antimicrobial Activity, Susceptibility, Administration and Dosage, Clinical Uses etc.

Ampicillin–sulbactam (AMP/S) is a beta-lactam/beta-lactamase inhibitor that was developed to overcome the increasing resistance of various bacteria to ampicillin. AMP/S is marketed under various trad

Mar 18,2022  API

Instructions of ?Pristinamycin

?Pristinamycin is a mixture of water-insoluble pristinamycin IA (PIA, 90–97%) and pristinamycin IIA (PIIA, 3–10%), derived from S. pristinaespiralis.

Mar 18,2022  API

Linezolid:U-100766

Linezolid (previously U-100766) is the first in a new class of completely synthetic antimicrobial agents, the oxazolidinones.

Mar 18,2022  API

The first glycylcycline---Tigecycline

Tigecycline is produced by Wyeth under the trade name of Tygacils. The modification of the tetracycline nucleus led to a reduction in tetracycline-specific efflux and ribosomal protection.

Mar 18,2022  API

Amoxicillin–clavulanic acid: Clinical Uses and Toxicity

Co-amoxiclav is widely used with good cure rates to treat urinary tract infections caused by both beta-lactamase-producing and nonproducing organisms, although in the latter case there is no advantage

Mar 18,2022  API

Amoxicillin–clavulanic acid: Antimicrobial Activity, Susceptibility, Administration and Dosage etc.

Amoxicillin–clavulanic acid (co-amoxiclav) is a combination product consisting of the semisynthetic antibiotic amoxicillin with the beta-lactamase inhibitor clavulanic acid as a potassium salt.

Mar 18,2022  API

Tazobactam: Antimicrobial Activity, Susceptibility, Administration and Dosage, Clinical Uses etc.

Being a beta-lactamase inhibitor, tazobactam is synergistic with many beta-lactamaselabile drugs, such as penicillin G, ampicillin, or piperacillin against many bacterial species which produce beta-l

Mar 18,2022  Inhibitors
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