Methyl 4-methoxyacetoacetate - application on synthetic works
Methyl 4-methoxyacetoacetate has been used in generation of a small focused library of diversely functionalized dihydropyrimidine derivatives via one-pot three-component Biginelli cyclocondensation of
Dec 24，2019 Chemical Reagents
How to prepare Cefditoren Pivoxil Dimer?
Cefditoren pivoxil is belong to cephalosporin drugs and is widely used for the treatment and prevention of various infectious diseases caused by pathogenic bacteria. Cefpodoxime proxetil is the third-
Dec 24，2019 Analytical Chemistry
What is the antioxidant activity of Caffeic acid during medication use?
Caffeic acid (CA, 3,4-dihydroxy-cinnamic acid) is an organic compound that is classified as a hydroxycinnamic acid. This yellow solid consists of both phenolic and acrylic functional groups, and it is
Dec 24，2019 API
How to prepare Bis(pinacolato)diboron?
Bis(pinacolato)diboron is a covalent compound containing two boron atoms and two pinacolato ligands. The pinacol groups are sometimes abbreviated as "pin", so the structure is sometimes represented as
Dec 24，2019 Organic Solvents
Loratinib – a cyclic ether used in the treatment of Non-small Cell Lung Cancer
Lorlatinib is a small molecule inhibitor of ALK and ROS1 kinase developed by Pfizer for the treatment of ALK-positive non-small cell lung cancer. It has a role as an antineoplastic agent and an EC 2.7
Dec 24，2019 Inhibitors
Aconine – an alkaloid from Aconitum species
Aconine is an alkaloid originally isolated from Aconitum species and active metabolite of aconitine [1]. It inhibits osteoclast differentiation of RANKL-stimulated RAW 264.7 cells and bone resorption
Dec 24，2019 Chinese Herbs
Tomatidine – a natural small molecule from tomato plants
Tomatidine is the aglycone derivative of tomatine. Tomatidine belongs to the chemical family known as Spirosolanes and Derivatives. These are steroidal alkaloids whose structure contains a spirosolane
Dec 24，2019 Natural Products
What can bis(trimethoxysilylpropyl)amine be used industrially?
Bis[3-(trimethoxysilyl)propyl]amine (BTMSPA) is a bis-amino silane which can be used as a water based coupling agent that promotes the adhesion between different materials to form a hybrid material. T
Dec 23，2019 Chemical Reagents
The role of 5-chloro-2-phenoxyphenylacetic acid as asenapine intermediate
5-chloro-2-phenoxyphenylacetic acid is the intermediate of asenapine synthesis, and Marco talked about the synthesis routes starting from 5-chloro-2-phenoxyphenylacetic acid as shown in scheme 1[2].
Dec 23，2019 Pharmaceutical intermediates
Intermediate role of 4,4-piperidinediol hydrochloride in organic synthesis
4-piperidone hydrochloride, monohydrate, also known as azinanone hydrochloride, is a derivative of piperidine used as an intermediate in manufacturing pharmaceutical drugs and chemicals [1].
Dec 23，2019 Organic Chemistry