AP26113- Pharmacodynamics

Brigatinib (AP26113) is a tyrosine kinase inhibitor with in vitro activity against a number of kinases, including ALK, ROS1, insulin-like growth factor-1 receptor (IGF-1R), FLT-3, and also epidermal g

Dec 13,2019  Inhibitors

BIBW2992 Dimaleate - Pharmacodynamics

Afatinib dimaleate (Tovok; BIBW2992; Gilotrif) is a salt form of Afatinib. Afatinib is a second-generation, orally administered, irreversible inhibitor of the ErbB family of tyrosine kinases.

Dec 13,2019  Inhibitors

Lenvatinib - pharmacodynamics

Lenvatinib (LenvimaTM) is a multitargeted receptor kinase inhibitor that inhibits the kinase activities of vascular endothelial-derived growth factor receptors.

Dec 13,2019  Inhibitors

Antifungal performance of Terbinafine hydrochloride

Terbinafine hydrochloride is a synthetic allylamine antifungal with a broad spectrum and used to treat dermatophyte infections of the toenail/fingernail, ringworm and jock itch[1].

Dec 12,2019  API

The use of pivaldehyde in organic synthesis

Pivaldehyde is an example of an aldehyde with the tertiary-butyl group (with 3 methyl groups), attached to the carbonyl (C=O) [1].

Dec 12,2019  Chemical Reagents

The application of 1-Dibenzofuranylboronic Acid in electronic devices

1-Dibenzofuranylboronic Acid is the reagent for electronic devices materials preparation. There are some synthesis routes to describe how do 1-dibenzofuranylboronic Acid works as the reagents for orga

Dec 12,2019  Pharmaceutical intermediates

The application of Sucrose octasulfate sodium salt in the digestive tract treatment

Sodium sucrose octasulfate is a chemical compound, and it has been used clinically for the prevention of gastrointestinal ulcers and was found to have cytoprotective effects.

Dec 12,2019  Saccharides

The role of 2-bromo-4-methylpropiophenone acting as intermediate for 4-MMC HCl synthesis

2-bromo-4-methylpropiophenone employed as an important intermediate for raw material for organic synthesis, agrochemical, pharmaceutical and dyestuff field.

Dec 12,2019  Organic Synthesis Intermediate

Intermediate role of 2-Chloro-5-iodopyrimidine in biological applications

2-Chloro-5-iodopyrimidine is 2-Chloro-5-iodopyridine is a halo-substituted pyridine, and it is used in biology application as synthesis intermediate in the multi-step synthesis.

Dec 12,2019  Pharmaceutical intermediates

Methylaminoformyl chloride-Application

Methylaminoformyl chloride(C2H4ClNO) is used as a reagent in the synthesis of acylprolinamides as a new class of peptide deformylase inhibitors with in vivo antibacterial activity.

Dec 12,2019  Pesticide Intermediates
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