BKM120: Biological Activity
BKM120 (PI3K inhibitor) is a small molecule orally available pan-I phosphoinositide 3-kinase inhibitor. Inositol mesylate 3-kinase inhibitors (PI3K inhibitors) are a class of medical drugs that inhibi
Dec 10，2019 Inhibitors
Biomedical properties of dacomitinib (PF299804)
Dacomitinib (PF299804), which name is (E)-N-[4-(3-chloro-4-fluoroanilino)-7- methoxyquinazolin-6-yl]-4-piperidin-1-ylbut-2-enamide, is a potent, orally available, highly selective, irreversible small-
Dec 10，2019 Inhibitors
Fluoranthene-3-carbaldehyde: A Synthetic Intermediate
Fluoranthene-3-carbaldehyde is belong to the polycyclic aromatic hydrocarbon (PAH). The molecule can be viewed as the fusion of naphthalene and benzene unit connected by a five-membered ring.
Dec 9，2019 Organic Chemistry
What is Monascin, and what is it used in medical treatment?
Monascin is an organic heterotricyclic compound that is 3a,4,8,9a-tetrahydro-2H-furo[3,2-g][2]benzopyran-2,9(3H)-dione that is substituted at positions 3, 6, and 9a by hexanoyl, (1E)-prop-1-en-1-yl an
Dec 9，2019 Inhibitors
What is Sildenafil used for?
Sildenafil, the first US FDA-approved, oral phosphodiesterase type-5 inhibitor, has revolutionized the treatment of erectile dysfunction sine its approval in 1998. Since sildenafil is a potent inhibit
Dec 9，2019 Hormones and the Endocrine System
4-Amino-2-chloropyridine: Application, Synthesis
4-Amino-2-chloropyridine is an important pharmaceutical and pesticide intermediate. It can synthesize N-(2-chloro-4-pyridyl)urea regulators that promote plant growth. It is also a key substance in the
Dec 9，2019 Pyridine Compound
Synthesis and Application of Tetrafluoropyridine
Pyridine and its derivatives have been developed and utilized relatively early at home and abroad. It is widely used in medicine, pesticides, rubber, dyes and other fields.
Dec 9，2019 Pharmaceutical intermediates
Medical applications of Creatine Phosphate Disodium Salt
Creatine phosphate belongs to the human body and is the most important type of energy supplier. It can provide energy support for various tissues and organs.
Dec 9，2019 Amino Acids and Derivatives
Synthesis of Glycyl-L-tyrosine
L-Tyrosine is an aromatic amino acid and one of the 20 amino acids that synthesize proteins. Tyrosine can be synthesized in the body, so it is a non-essential amino acid.
Dec 9，2019 Amino Acids and Derivatives
Synthesis and Application of Di-tert-butyl disulfide
Di-tert-butyl disulfide is an important organic intermediate.It is an important raw material for the synthesis of disulfide bond-containing sulfinyl and oxythio compounds. It can be used as a vulcaniz
Dec 9，2019 Organic Synthesis Intermediate